Intellectual curiosity has always been one of the major driving forces leading to new
advances in chemistry. At the onset of the 20th century, the fact that biaryls could be optically …

This study describes some characteristics of the Rubiaceae family pertaining to the
occurrence and distribution of secondary metabolites in the main genera of this family. It …

The biaryl axis is the joint central structural element of a broad variety of structurally (in
particular stereochemically) and biosynthetically interesting as well as pharmacologically …

The catalytic and selective construction of carbon–carbon bonds for the generation of
complex molecules is one of the most important tasks in organic chemistry. This was clearly …

Medicinal plants constitute a source for designing clinically useful drugs targeting diseases
through various mechanisms. Plant secondary metabolites can be used as lead compounds …

The chapter “Atropisomerism and axial chirality in heteroaromatic compounds” provides a
summary of the present knowledge of this important topic. The structure of the chapter is: first …

Bisindole natural products consist of two monomeric indole alkaloid units as their obligate
constituents. Bisindoles are more potent with respect to their biological activity than their …

Non-phenolic oxidative coupling: The first total synthesis of the C-2 symmetric indole
alkaloid P-(+)-dispegatrine (1) is reported. A late-stage thallium (III) acetate mediated …

Almost 50 species of Ophiorrhiza plants were reviewed in this work and the main objective is
to critically analyse their distribution, phytochemical content, biological activity, and …

The first regio-and stereocontrolled total synthesis of the bisphenolic, bisquaternary alkaloid
(+)-dispegatrine (1) has been accomplished in an overall yield of 8.3%(12 reaction vessels) …