Photobleaching of organic fluorophores: quantitative characterization, mechanisms, protection

AP Demchenko - Methods and applications in fluorescence, 2020 - iopscience.iop.org
Photochemical stability is one of the most important parameters that determine the
usefulness of organic dyes in different applications. This Review addresses key factors that …

Molecular communication and nanonetwork for targeted drug delivery: A survey

UAK Chude-Okonkwo, R Malekian… - … Surveys & Tutorials, 2017 - ieeexplore.ieee.org
Molecular communication (MC) and molecular network (MN) are communication paradigms
that use biochemical signaling to achieve information exchange among naturally and …

ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors

Y Hong, BL Walling, HR Kim, WS Serratelli… - Nature …, 2023 - nature.com
Adoptive transfer of genetically engineered chimeric antigen receptor (CAR) T cells is
becoming a promising treatment option for hematological malignancies. However, T cell …

Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex

N Khalilgharibi, J Fouchard, N Asadipour, R Barrientos… - Nature physics, 2019 - nature.com
Epithelial monolayers are one-cell-thick tissue sheets that line most of the body surfaces,
separating internal and external environments. As part of their function, they must withstand …

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

M Fritzsche, RA Fernandes, VT Chang… - Science …, 2017 - science.org
T cell activation and especially trafficking of T cell receptor microclusters during
immunological synapse formation are widely thought to rely on cytoskeletal remodeling …

Dynamics of proteins in solution

M Grimaldo, F Roosen-Runge, F Zhang… - Quarterly Reviews of …, 2019 - cambridge.org
The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …

EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data

G Koulouras, A Panagopoulos… - Nucleic acids …, 2018 - academic.oup.com
Understanding protein dynamics is crucial in order to elucidate protein function and
interactions. Advances in modern microscopy facilitate the exploration of the mobility of …

Actin kinetics shapes cortical network structure and mechanics

M Fritzsche, C Erlenkämper, E Moeendarbary… - Science …, 2016 - science.org
The actin cortex of animal cells is the main determinant of cellular mechanics. The
continuous turnover of cortical actin filaments enables cells to quickly respond to stimuli …

Quantitative analysis reveals that actin and Src-family kinases regulate nuclear YAP1 and its export

N Ege, AM Dowbaj, M Jiang, M Howell, S Hooper… - Cell systems, 2018 - cell.com
The transcriptional regulator YAP1 is critical for the pathological activation of fibroblasts. In
normal fibroblasts, YAP1 is located in the cytoplasm, while in activated cancer-associated …

Self-organizing actin patterns shape membrane architecture but not cell mechanics

M Fritzsche, D Li, H Colin-York, VT Chang… - Nature …, 2017 - nature.com
Cell-free studies have demonstrated how collective action of actin-associated proteins can
organize actin filaments into dynamic patterns, such as vortices, asters and stars. Using …