[HTML][HTML] Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics

X Feng, A Sureda, S Jafari, Z Memariani, D Tewari… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberis Vulgaris and Berberine: An Update Review

M Imenshahidi, H Hosseinzadeh - Phytotherapy research, 2016 - Wiley Online Library
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Expatiating the pharmacological and nanotechnological aspects of the alkaloidal drug berberine: current and future trends

T Behl, S Singh, N Sharma, I Zahoor, A Albarrati… - Molecules, 2022 - mdpi.com
Traditionally, herbal compounds have been the focus of scientific interest for the last several
centuries, and continuous research into their medicinal potential is underway. Berberine …

Role of berberine in Alzheimer's disease

Z Cai, C Wang, W Yang - Neuropsychiatric disease and treatment, 2016 - Taylor & Francis
Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways

W Yu, M Sheng, R Xu, J Yu, K Cui, J Tong, L Shi… - Journal of translational …, 2013 - Springer
Background Ischemia/reperfusion injury plays a crucial role in renal transplantation, and
represents a significant risk factor for acute renal failure and delayed graft function. The …

Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: up-regulated pAkt, pGSK and pCREB, down-regulated NF-κB …

X Zhang, X Zhang, C Wang, Y Li, L Dong, L Cui… - Brain research, 2012 - Elsevier
BACKGROUND: Berberine (BBR) has gained attention for its vast beneficial biological
effects through immunomodulation, anti-inflammatory and anti-apoptosis properties …

Berberine: a plant-derived alkaloid with therapeutic potential to combat Alzheimer's disease

AK Singh, SK Singh, MK Nandi… - … System Agents in …, 2019 - ingentaconnect.com
Berberine (a protoberberine isoquinoline alkaloid) has shown promising pharmacological
activities, including analgesic, anti-inflammatory, anticancer, antidiabetic, anti …

Therapeutic potential of berberine against neurodegenerative diseases

WX Jiang, SH Li, XJ Li - Science China Life Sciences, 2015 - Springer
Berberine (BBR) is an organic small molecule isolated from various plants that have been
used in traditional Chinese medicine. Isolation of this compound was its induction into …

Neuroprotective effect and preparation methods of berberine

YX Sunhe, YH Zhang, RJ Fu, DQ Xu… - Frontiers in …, 2024 - frontiersin.org
Berberine (BBR) is a natural alkaloid, which has played an important role in the field of
medicine since its discovery in the late 19th century. However, the low availability of BBR in …

Mitochondria and NMDA receptor-dependent toxicity of berberine sensitizes neurons to glutamate and rotenone injury

K Kysenius, CA Brunello, HJ Huttunen - PloS one, 2014 - journals.plos.org
The global incidence of metabolic and age-related diseases, including type 2 diabetes and
Alzheimer's disease, is on the rise. In addition to traditional pharmacotherapy, drug …