Immune checkpoint blockage has been considered a breakthrough in cancer treatment,
achieving encouraging anti-tumor effects in some advanced solid malignancies. However …

Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

ZEB1 and ZEB2 are zinc-finger E homeobox-binding transcription factors best known for
their role in driving epithelial to mesenchymal transition. However, in recent years our …

Zinc finger E-box binding homeobox 1 (ZEB1) is a master modulator of the epithelial–
mesenchymal transition (EMT), a process whereby epithelial cells undergo a series of …

The transcription factor zinc finger E-box binding homeobox 1 (ZEB1) is a critical inducer of
epithelial mesenchymal transformation (EMT) and plays a robust role in tumor metastasis. It …

Mycobacterium tuberculosis (Mtb) defends host-mediated killing by repressing the
autophagolysosome machinery. For the first time, we report NCoR1 co-repressor as a …

The epithelial to mesenchymal transition (EMT) is a fundamental developmental process
essential for normal embryonic development. It is also important during various pathogenic …

Simple Summary Angiotensin inhibitors are broadly applied in the treatment of renal and
cardiovascular diseases. This review aims to show that these drugs have also been …

Fascin protein is the main actin-bundling protein in filopodia and invadopodia, which are
critical for tumor cell migration, invasion, and metastasis. Small-molecule fascin inhibitors …

Simple Summary While invading tumor-adjacent tissue, cancer cells often undergo epithelial-
mesenchymal transition (EMT). A mechanistic understanding of EMT may therefore improve …