The nuclear factor–kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease

B Pamukcu, GYH Lip, E Shantsila - Thrombosis research, 2011 - Elsevier
Nuclear factor kappa B (NFκB) is a transcription factor belonging to 'Rel'family that
represents a crucial intracellular signal transduction system involved in several inflammatory …

[HTML][HTML] Hegemony of inflammation in atherosclerosis and coronary artery disease

A Attiq, S Afzal, W Ahmad, M Kandeel - European Journal of Pharmacology, 2024 - Elsevier
Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …

Intracardiac and extracardiac markers of inflammation during atrial fibrillation

GM Marcus, LM Smith, K Ordovas, MM Scheinman… - Heart rhythm, 2010 - Elsevier
BACKGROUND: A decrease in inflammation after cure of atrial arrhythmias suggests that
such arrhythmias are proinflammatory, and lower inflammatory marker levels in the coronary …

CRP and the risk of atherosclerotic events

P Calabrò, E Golia, ETH Yeh - Seminars in immunopathology, 2009 - Springer
A large body of literature supports the idea that inflammation plays a pivotal role in all
phases of atherosclerosis, from the fatty streak lesion formation to the acute coronary event …

The role of autophagy in cardiovascular disease: Cross-interference of signaling pathways and underlying therapeutic targets

B Jiang, X Zhou, T Yang, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic proteins
and organelles, which realizes the metabolic needs of cells and the renewal of organelles …

The connection between C‐reactive protein and atherosclerosis

SK Singh, MV Suresh, B Voleti, A Agrawal - Annals of medicine, 2008 - Taylor & Francis
The connection between C‐reactive protein (CRP) and atherosclerosis lies on three
grounds. First, the concentration of CRP in the serum, which is measured by using highly …

Human C-reactive protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats

U Singh, MR Dasu, PG Yancey, A Afify, S Devaraj… - Journal of lipid …, 2008 - ASBMB
C-reactive protein (CRP) is present in the atherosclerotic plaques and appears to promote
atherogenesis. Intraplaque CRP colocalizes with oxidized low density lipoprotein (OxLDL) …

Reappraisal of inflammatory biomarkers in heart failure

T Chaikijurajai, WHW Tang - Current heart failure reports, 2020 - Springer
Abstract Purpose of Review Inflammation has been shown to be an important factor in the
development and progression of heart failure (HF), regardless of the etiology. There have …

Mechanisms behind the atherothrombotic effects of acrolein, a review

MR Zirak, S Mehri, A Karimani, M Zeinali… - Food and Chemical …, 2019 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The majority of
cardiovascular complications are secondary to atherosclerosis. Extensive evidence has …

Identification and analysis of key genes associated with acute myocardial infarction by integrated bioinformatics methods

S Guo, J Wu, W Zhou, X Liu, Y Liu, J Zhang, S Jia, J Li… - Medicine, 2021 - journals.lww.com
Background: Acute myocardial infarction (AMI) is a common disease leading threat to
human health around the world. Here we aimed to explore new biomarkers and potential …