Biochemical markers of aging for longitudinal studies in humans

PM Engelfriet, EHJM Jansen, HSJ Picavet… - Epidemiologic …, 2013 - academic.oup.com
Much progress has been made in the past decades in unraveling the mechanisms that are
responsible for aging. The discovery that particular gene mutations in experimental species …

Heterogeneity of human aging and its assessment

A Mitnitski, SE Howlett… - Journals of Gerontology …, 2017 - academic.oup.com
Understanding the heterogeneity in health of older adults is a compelling question in the
biology of aging. We analyzed the performance of five measures of health heterogeneity …

Dynamics of biomarkers in relation to aging and mortality

KG Arbeev, SV Ukraintseva, AI Yashin - Mechanisms of ageing and …, 2016 - Elsevier
Contemporary longitudinal studies collect repeated measurements of biomarkers allowing
one to analyze their dynamics in relation to mortality, morbidity, or other health-related …

[HTML][HTML] Fasting blood glucose as a predictor of mortality: Lost in translation

DL Palliyaguru, EJ Shiroma, JK Nam, E Duregon… - Cell metabolism, 2021 - cell.com
Aging leads to profound changes in glucose homeostasis, weight, and adiposity, which are
considered good predictors of health and survival in humans. Direct evidence that these age …

Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study

SW Yi, S Park, Y Lee, HJ Park, B Balkau, JJ Yi - Scientific reports, 2017 - nature.com
The association of fasting glucose with the risk of death according to sex and age remains
unclear, and insufficient information is available on sex-and age-specific glucose …

“Physiological Dysregulation” as a promising measure of robustness and resilience in studies of aging and a new indicator of preclinical disease

KG Arbeev, SV Ukraintseva, O Bagley… - The Journals of …, 2019 - academic.oup.com
Recently suggested novel implementation of the statistical distance measure (DM) for
evaluating “physiological dysregulation”(PD) in aging individuals (based on measuring …

Age trajectories of physiological indices in relation to healthy life course

KG Arbeev, SV Ukraintseva, I Akushevich… - Mechanisms of Ageing …, 2011 - Elsevier
We analysed relationship between the risk of onset of “unhealthy life”(defined as the onset of
cancer, cardiovascular diseases, or diabetes) and longitudinal changes in body mass index …

[图书][B] Жизнь без старости

М Скулачев, В Скулачев, Б Фенюк - 2017 - books.google.com
Как продлить молодость и дожить до 122 лет? Ответ на этот вопрос дали не фантасты,
а академик РАН Владимир Скулачев и ведущие российские биохимики. После …

The convergence of type 1 and type 2 diabetes in childhood: the accelerator hypothesis

TJ Wilkin - Pediatric diabetes, 2012 - Wiley Online Library
It seems likely that type 1 and type 2 diabetes lie at different points of the same spectrum,
separated by the misunderstanding that one belongs to childhood and the other to …

Hemoglobin A1c, fasting plasma glucose, and 2-hour plasma glucose distributions in US population subgroups: NHANES 2005–2010

A Menke, KF Rust, PJ Savage, CC Cowie - Annals of epidemiology, 2014 - Elsevier
Purpose Although mean concentrations of hemoglobin A1c (A1C), fasting plasma glucose,
and 2-hour plasma glucose differ by demographics, it is unclear what other characteristics of …