Infection with Burkholderia pseudomallei can result in asymptomatic seroconversion, a
single skin lesion that may or may not heal spontaneously, a pneumonia which can be …

Melioidosis, caused by the gram-negative saprophyte Burkholderia pseudomallei, is a
disease of public health importance in southeast Asia and northern Australia that is …

Background Over 20 years, from October 1989, the Darwin prospective melioidosis study
has documented 540 cases from tropical Australia, providing new insights into epidemiology …

Here we report on the development of a discriminatory real-time assay for the rapid
identification of Burkholderia pseudomallei isolates and the evaluation of this assay for …

Background Melioidosis is a severe infectious disease caused by Burkholderia
pseudomallei, a Gram-negative bacillus classified by the National Institute of Allergy and …

Objectives The aims of this study were to describe the epidemiology of melioidosis in
tropical northern Australia and to assess the importance of defined risk factors. Methods The …

The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …

Abstract The US Public Health Emergency Medical Countermeasures Enterprise convened
subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus …

Background Toll-like receptors (TLRs) are essential in host defense against pathogens by
virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as …

Burkholderia pseudomallei causes the disease melioidosis in humans and is classified as a
category B select agent. Research utilizing this pathogen is highly regulated in the United …