Advances and opportunities in process analytical technologies for viral vector manufacturing
Viral vectors are an emerging, exciting class of biologics whose application in vaccines,
oncology, and gene therapy has grown exponentially in recent years. Following first …
oncology, and gene therapy has grown exponentially in recent years. Following first …
Peptide ligands targeting the vesicular stomatitis virus G (VSV‐G) protein for the affinity purification of lentivirus particles
E Barbieri, GN Mollica, BD Moore… - Biotechnology and …, 2024 - Wiley Online Library
The recent uptick in the approval of ex vivo cell therapies highlights the relevance of
lentivirus (LV) as an enabling viral vector of modern medicine. As labile biologics, however …
lentivirus (LV) as an enabling viral vector of modern medicine. As labile biologics, however …
Peptide ligands for the universal purification of exosomes by affinity chromatography
RE Kilgore, BD Moore, SA Sripada… - Biotechnology and …, 2024 - Wiley Online Library
Exosomes are gaining prominence as vectors for drug delivery, vaccination, and
regenerative medicine. Owing to their surface biochemistry, which reflects the parent cell …
regenerative medicine. Owing to their surface biochemistry, which reflects the parent cell …
Mixed-mode size-exclusion silica resin for polishing human antibodies in flow-through mode
The polishing step in the downstream processing of therapeutic antibodies removes residual
impurities from Protein A eluates. Among the various classes of impurities, antibody …
impurities from Protein A eluates. Among the various classes of impurities, antibody …
A Batch Technique for Connecting Multimodal Ligand Chemistry to Chromatographic Separability
E Denbaum - 2024 - search.proquest.com
This dissertation describes the development and utilization of a high-throughput parallel
batch adsorption screen with sequential salt step increases to rapidly generate protein …
batch adsorption screen with sequential salt step increases to rapidly generate protein …