Ticks are blood-sucking arthropods that have developed myriad of strategies to get a blood
meal from the vertebrate host. They first attach to the host skin, select a bite site for a blood …

Highlights•Arthropod exosomes carry viral RNA genomes and proteins.•Arthropod
exosomes facilitate sequential dissemination of arboviruses within vector and from vector to …

The microRNAs (miRNAs) are important regulators of gene expression. In this study, we
provide evidence for the first time to show that rickettsial pathogen Anaplasma …

Human anaplasmosis caused by Anaplasma phagocytophilum is one of the most common
tick-borne diseases in the United States. The black-legged ticks, Ixodes scapularis, vector …

Our previous study showed that cells from medically important arthropods, such as ticks,
secrete extracellular vesicles (EVs) including exosomes that mediate transmission of …

Anaplasma phagocytophilum modulates various cell signaling pathways in mammalian cells
for its survival. In this study, we report that A. phagocytophilum modulates tick tryptophan …

The invasive Asian longhorned tick Haemaphysalis longicornis that vectors and transmits
several animal pathogens is significantly expanding in the United States. Recent studies …

Although tick-borne infectious diseases threaten human and animal health worldwide, with
constantly increasing incidence, little knowledge is available regarding vector–pathogen …

Ixodes scapularis ticks acquire several pathogens from reservoir animals and transmit them
to humans. Development of an animal model to study acquisition/transmission dynamics of …

Ticks are important vectors that transmit several pathogens including human anaplasmosis
agent, Anaplasma phagocytophilum. This bacterium is an obligate intracellular rickettsial …