Isolated growth hormone deficiency (GHD) in childhood and adolescence: recent advances

KS Alatzoglou, EA Webb, P Le Tissier… - Endocrine …, 2014 - academic.oup.com
The diagnosis of GH deficiency (GHD) in childhood is a multistep process involving clinical
history, examination with detailed auxology, biochemical testing, and pituitary imaging, with …

[HTML][HTML] Implication of sphingosin-1-phosphate in cardiovascular regulation

N Li, F Zhang - Frontiers in bioscience (Landmark edition), 2016 - ncbi.nlm.nih.gov
Abstract Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite generated
by phosphorylation of sphingosine catalyzed by sphingosine kinase. S1P acts mainly …

Puerarin attenuates diabetic kidney injury through interaction with guanidine nucleotide‐binding protein Gi subunit alpha‐1 (Gnai1) subunit

Q Zhu, S Yang, C Wei, G Lu, K Lee… - Journal of Cellular …, 2022 - Wiley Online Library
Radix puerariae, a traditional Chinese herbal medication, has been used to treat patients
with diabetic kidney disease (DKD). Our previous studies demonstrated that puerarin, the …

Control of firing patterns through modulation of axon initial segment T‐type calcium channels

KJ Bender, VN Uebele, JJ Renger… - The Journal of …, 2012 - Wiley Online Library
Non‐technical summary Spontaneous bursting, in which neurons spontaneously fire
clusters of action potentials, underlies a variety of neuronal functions, including breathing …

Anandamide Reduces Intracellular Ca2+ Concentration through Suppression of Na+/Ca2+ Exchanger Current in Rat Cardiac Myocytes

Q Li, N Cui, Y Du, H Ma, Y Zhang - PloS one, 2013 - journals.plos.org
Purpose Anandamide, one of the endocannabinoids, has been reported to exhibit
cardioprotective properties, particularly in its ability to limit the damage produced by …

Lysophospholipids Modulate Voltage-Gated Calcium Channel Currents in Pituitary Cells; Effects of Lipid-Stress

G Ben-Zeev, M Telias, D Bert, I Nussinovitch - Biophysical Journal, 2010 - cell.com
Voltage-gated calcium channels (VGCC) are osmosensitive. To test the hypothesis that this
property of VGCCs stems from their susceptibility to alterations in the mechanical properties …

Pharmacogenetics of D2 dopamine receptor gene in prolactin-secreting pituitary adenomas

M Filopanti, AG Lania, A Spada - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: Dopamine-agonists are the treatment of choice of prolactin-secreting
pituitary adenomas (PRL-omas). Their actions on D2 dopamine receptor (DRD2) and the …

[HTML][HTML] Review of serum prolactin levels as an antipsychotic-response biomarker

JM Gault, AM Nussbaum - Open access journal of translational …, 2018 - ncbi.nlm.nih.gov
Antipsychotics acting as antagonists at dopamine D2 receptors concentrated in the striatum
are the cornerstone of effective treatment of psychosis. Substantial progress in treating …

Paliperidone and aripiprazole differentially affect the strength of calcium-secretion coupling in female pituitary lactotrophs

M Kucka, M Tomić, I Bjelobaba, SS Stojilkovic… - Scientific reports, 2015 - nature.com
Hyperprolactinemia is a common adverse in vivo effect of antipsychotic medications that are
used in the treatment of patients with schizophrenia. Here, we compared the effects of two …

Mechanism and function of phasic firing in vasopressin‐releasing magnocellular neurosecretory cells

ZS Thirouin, CW Bourque - Journal of Neuroendocrinology, 2021 - Wiley Online Library
Magnocellular neurosecretory cells that release vasopressin (MNCVP) from axon terminals
in the neurohypophysis display a unique pattern of action potential firing termed phasic …