One biomarker does not fit all: tailoring anti-infective therapy through utilization of procalcitonin and other specific biomarkers

L Essmann, Y Wirz, C Gregoriano… - Expert Review of …, 2023 - Taylor & Francis
Introduction Considering the ongoing increase in antibiotic resistance, the importance of
judicious use of antibiotics through reduction of exposure is crucial. Adding procalcitonin …

Blood culture-free ultra-rapid antimicrobial susceptibility testing

TH Kim, J Kang, H Jang, H Joo, GY Lee, H Kim, U Cho… - Nature, 2024 - nature.com
Abstract Treatment assessment and patient outcome for sepsis depend predominantly on
the timely administration of appropriate antibiotics,–. However, the clinical protocols used to …

Electrochemical point-of-care devices for the diagnosis of sepsis

E Valera, V Kindratenko, AM Jankelow… - Current opinion in …, 2023 - Elsevier
Sepsis is a life-threatening dysfunction of organ systems caused by a dysregulated immune
system because of an infectious process. It remains one of the leading causes of hospital …

Affinity molecular assay for detecting Candida albicans using chitin affinity and RPA-CRISPR/Cas12a

S Shen, W Wang, Y Ma, S Wang, S Zhang… - Nature …, 2024 - nature.com
Invasive fungal infections (IFIs) pose a significant threat to immunocompromised individuals,
leading to considerable morbidity and mortality. Prompt and accurate diagnosis is essential …

Seamless Integration of Rapid Separation and Ultrasensitive Detection for Complex Biological Samples Using Multistage Annular Functionalized Carbon Nanotube …

L Li, J Zhang, Z Jiao, X Zhou, L Ren… - Advanced …, 2024 - Wiley Online Library
Efficient separation, enrichment, and detection of bacteria in diverse media are pivotal for
identifying bacterial diseases and their transmission pathways. However, conventional …

[HTML][HTML] Research progress on detection of pathogens in medical wastewater by electrochemical biosensors

B Chen, J He, K Tian, J Qu, L Hong, Q Lin, K Yang… - Molecules, 2024 - mdpi.com
The detection of pathogens in medical wastewater is crucial due to the high content of
pathogenic microorganisms that pose significant risks to public health and the environment …

Self-Interference Digital Optofluidic Genotyping for Integrated and Automated Label-Free Pathogen Detection

T Zhou, R Fu, J Hou, F Yang, F Chai, Z Mao… - ACS …, 2024 - ACS Publications
Pathogen, prevalent in both natural and human environments, cause approximately 4.95
million deaths annually, ranking them among the top contributors to global mortality …

A biphasic accelerated strand exchange amplification strategy for culture-independent and rapid detection of Salmonella enterica in food samples

X Zhang, X Wang, B Shi, J Li, Y Fan, Y Li, C Shi… - Analytical …, 2024 - pubs.rsc.org
Salmonella enterica is a common foodborne pathogen that can cause food poisoning in
humans. The organism also infects and causes disease in animals. Rapid and sensitive …

Direct identification of pathogens via microbial cellular DNA in whole blood by MeltArray

J Song, S Lin, L Zhu, Y Lin, W An, J Zhang… - Microbial …, 2024 - Wiley Online Library
Rapid identification of pathogens is critical for early and appropriate treatment of
bloodstream infections. The various culture‐independent assays that have been developed …

Culture‐free biphasic approach for early sepsis detection: A true game changer

H Mushahid, S Mughal, MO Sonija… - Health Science …, 2024 - ncbi.nlm.nih.gov
Sepsis is a life‐threatening clinical syndrome that can be defined as infection‐induced
physiologic, pathologic, and biochemical abnormalities—the source of which may be a …