Clostridium difficile infection
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …
threatening, especially in elderly people and in patients who have dysbiosis of the gut …
Risk Factors for Recurrence, Complications and Mortality in Clostridium difficile Infection: A Systematic Review
Background Clostridium difficile infection (CDI) can lead to complications, recurrence, and
death. Numerous studies have assessed risk factors for these unfavourable outcomes, but …
death. Numerous studies have assessed risk factors for these unfavourable outcomes, but …
Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection: a randomized clinical trial
CH Lee, T Steiner, EO Petrof, M Smieja, D Roscoe… - Jama, 2016 - jamanetwork.com
Importance Clostridium difficileinfection (CDI) is a major burden in health care and
community settings. CDI recurrence is of particular concern because of limited treatment …
community settings. CDI recurrence is of particular concern because of limited treatment …
Risk factors for mortality among children younger than age 5 years with severe diarrhea in low-and middle-income countries: Findings from the world health …
RM Hartman, AL Cohen, S Antoni… - Clinical Infectious …, 2023 - academic.oup.com
Background Diarrhea is the second leading cause of death in children younger than 5 years
of age globally. The burden of diarrheal mortality is concentrated in low-resource settings …
of age globally. The burden of diarrheal mortality is concentrated in low-resource settings …
Anti-infective activities of lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents
V Liévin-Le Moal, AL Servin - Clinical microbiology reviews, 2014 - Am Soc Microbiol
SUMMARY A vast and diverse array of microbial species displaying great phylogenic,
genomic, and metabolic diversity have colonized the gastrointestinal tract. Resident …
genomic, and metabolic diversity have colonized the gastrointestinal tract. Resident …
Comparative effectiveness of vancomycin and metronidazole for the prevention of recurrence and death in patients with Clostridium difficile infection
VW Stevens, RE Nelson… - JAMA internal …, 2017 - jamanetwork.com
Importance Metronidazole hydrochloride has historically been considered first-line therapy
for patients with mild to moderateClostridium difficileinfection (CDI) but is inferior to …
for patients with mild to moderateClostridium difficileinfection (CDI) but is inferior to …
Antimicrobial stewardship in the emergency department
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Estimating excess length of stay due to healthcare-associated infections: a systematic review and meta-analysis of statistical methodology
Background Healthcare-associated infection (HCAI) affects millions of patients worldwide.
HCAI is associated with increased healthcare costs, owing primarily to increased hospital …
HCAI is associated with increased healthcare costs, owing primarily to increased hospital …
Understanding decisions about antibiotic prescribing in ICU: an application of the necessity concerns framework
Background Antibiotics are extensively prescribed in intensive care units (ICUs), yet little is
known about how antibiotic-related decisions are made in this setting. We explored how …
known about how antibiotic-related decisions are made in this setting. We explored how …
The Efficacy and Safety of Fecal Microbiota Transplant for Recurrent Clostridiumdifficile Infection: Current Understanding and Gap Analysis
MH Wilcox, BH McGovern… - Open forum infectious …, 2020 - academic.oup.com
The leading risk factor for Clostridioides (Clostridium) difficile infection (CDI) is broad-
spectrum antibiotics, which lead to low microbial diversity, or dysbiosis. Current therapeutic …
spectrum antibiotics, which lead to low microbial diversity, or dysbiosis. Current therapeutic …