Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …

Normal cell-cycle progression is a crucial task for every multicellular organism, as it
determines body size and shape, tissue renewal and senescence, and is also crucial for …

Tumours progress despite being infiltrated by tumour-specific effector T cells. Tumours
contain areas of cellular necrosis, which are associated with poor survival in a variety of …

Potassium channels are pore-forming transmembrane proteins that regulate a multitude of
biological processes by controlling potassium flow across cell membranes. Aberrant …

Changes of the electrical charges across the surface cell membrane are absolutely
necessary to maintain cellular homeostasis in physiological as well as in pathological …

VSMC s in resistance arteries and arterioles express a diverse array of KV channels with
members of the KV 1, KV 2 and KV 7 families being particularly important. Members of the …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

Voltage-gated potassium channel Kv1. 3 is an integral membrane protein, which is
selectively permeable for potassium ions and is activated upon a change of membrane …

Ion channels allow the flux of specific ions across biological membranes, thereby
determining ion homeostasis within the cells. Voltage-gated potassium-selective ion …

Kv1. 3 channels are involved in the switch to proliferation of normally quiescent cells, being
implicated in the control of cell cycle in many different cell types and in many different ways …