Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …

Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still
severely limited by a lack of suitable organ donors. Kidneys from donation after circulatory …

Normothermic machine perfusion (NMP) technologies are emerging as an important adjunct
in organ preservation and transplantation. NMP can enable the reduction or avoidance of …

Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

Because of the high demand of organs, the usage of marginal grafts has increased. These
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …

The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …

Background The 5-year graft survival rate of donor kidneys transplanted in the
Eurotransplant Senior Program (ESP) is only 47 per cent. Normothermic machine perfusion …

Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

Background. The optimal method of oxygen delivery to donor kidneys during ex vivo
machine perfusion has not been established. We have recently reported the beneficial …