Diet, stress and mental health

JD Bremner, K Moazzami, MT Wittbrodt, JA Nye… - Nutrients, 2020 - mdpi.com
Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

[HTML][HTML] Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies

WS Harris, NL Tintle, F Imamura, F Qian… - Nature …, 2021 - nature.com
The health effects of omega-3 fatty acids have been controversial. Here we report the results
of a de novo pooled analysis conducted with data from 17 prospective cohort studies …

Protective effects of omega-3 fatty acids in cancer-related complications

RDS Freitas, MM Campos - Nutrients, 2019 - mdpi.com
Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …

[HTML][HTML] The anti-inflammatory role of omega-3 polyunsaturated fatty acids metabolites in pre-clinical models of psychiatric, neurodegenerative, and neurological …

J Giacobbe, B Benoiton, P Zunszain… - Frontiers in …, 2020 - frontiersin.org
Inflammation has been identified as one of the main pathophysiological mechanisms
underlying neuropsychiatric and neurodegenerative disorders. Despite the role of …

[HTML][HTML] Brain docosahexaenoic acid uptake and metabolism

RJS Lacombe, R Chouinard-Watkins… - Molecular Aspects of …, 2018 - Elsevier
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy

J Dort, Z Orfi, P Fabre, T Molina, TC Conte… - Nature …, 2021 - nature.com
Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic
inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular …

N-3 polyunsaturated fatty acids and the resolution of neuroinflammation

C Joffre, C Rey, S Layé - Frontiers in pharmacology, 2019 - frontiersin.org
In the past few decades, as a result of their anti-inflammatory properties, n-3 long chain
polyunsaturated fatty acids (n-3 LC-PUFAs), have gained greater importance in the …

Novel pharmacological approaches to the treatment of depression

E Elias, AY Zhang, MT Manners - Life, 2022 - mdpi.com
Major depressive disorder is one of the most prevalent mental health disorders. Monoamine-
based antidepressants were the first drugs developed to treat major depressive disorder …

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine

S Deyama, M Kondo, S Shimada, K Kaneda - Translational Psychiatry, 2022 - nature.com
Ketamine, an N-methyl-D-aspartate receptor antagonist, exerts rapid and sustained
antidepressant actions. Preclinical studies demonstrated that the release of brain-derived …