Paracellular permeability across epithelial and endothelial cells is, in large part, regulated
by apical intercellular junctions also referred to as tight junctions (TJs). These junctions …

Blindness poses a growing global challenge, with approximately 26% of cases attributed to
degenerative retinal diseases. While gene therapy, optogenetic tools, photosensitive …

Diabetic retinopathy (DR) is a devastating complication of diabetes, having extensive and
resilient effects on those who suffer from it. As yet, the underlying cell mechanisms of this …

Extracellular vesicles (EVs) are membrane-bound particles released by cells to perform
multitudes of biological functions. Owing to their significant implications in diseases, the …

Retinal degenerative diseases, including diabetic retinopathy (DR) and age-related macular
degeneration (AMD), loom as threats to vision, causing detrimental effects on the structure …

Diabetic complications, especially diabetic retinopathy, diabetic nephropathy and painful
diabetic neuropathy, account for a large portion of patients with diabetes and display rising …

Extracellular vesicles (EVs) are released as highly stable lipid bilayer particles carrying
proteins, lipids, glycans and miRNAs. The contents of EVs vary based on the cellular origin …

Diabetic retinopathy (DR) is a leading cause of blindness, yet its molecular mechanisms are
unclear. Extracellular vesicles (EVs) contribute to dysfunction in DR, but the characteristics …

Despite progress in the management of patients with retinal vascular and degenerative
diseases, there is still an unmet clinical need for safe and effective therapeutic options with …

Our previous study demonstrated that combined transplantation of bone marrow–derived
mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal …