K Matsuda, K Fujita, T Wakimoto - Journal of Industrial …, 2021 - academic.oup.com
Penicillin-binding protein-type thioesterases (PBP-type TEs) are a recently identified group of peptide cyclases that catalyze head-to-tail macrolactamization of nonribosomal peptides …
H Wang, X Yi, Z Zhou, J Yang, Y Pei, S Shi, C Gao… - Tetrahedron, 2023 - Elsevier
Whole-genome sequencing and bioinformatics analyses have shown that the potential of synthesizing secondary metabolites from marine-derived Streptomyces has been …
Burkholderia pseudomallei is the Gram-negative bacterium that cause infection termed “Melioidosis”[ 1, 2]. It widely dominates soil as well as water surface and could easily be …
D Carretero-Molina, FJ Ortiz-López… - Journal of Natural …, 2021 - ACS Publications
Pentaminomycins F–H (1–3), a group of three new hydroxyarginine-containing cyclic pentapeptides, were isolated from cultures of a Streptomyces cacaoi subsp. cacaoi strain …
Microorganisms, as an immense treasure trove of natural products, have consistently been a crucial source for researchers to explore and develop new natural products. Currently, the …
The emergence of antibiotic resistant pathogenic strains, especially Gram-negative bacteria, has seriously increased in the last decades, endangering the efficiency of the antibiotics …
The relentless emergence of bacterial resistance to current antibiotics poses a significant health treat, making the development of new effective treatments of vital importance. In this …
S Cociancich, V Leclère - Microorganisms, 2022 - mdpi.com
Microbial secondary metabolites are natural products that display various therapeutical or agrochemical relevant activities (eg, antibiotics, antifungal, or antiproliferative agents …