As angiogenesis is essential for tumor growth and metastasis, controlling tumor-associated
angiogenesis is a promising tactic in limiting cancer progression. The tumor …

Melanoma is a life-threatening malignancy with poor prognosis and a relatively high burden
of mortality in advanced stages. The efficacy of current available therapeutic strategies is …

MicroRNAs represent a class of small RNAs derived from polymerase II controlled
transcriptional regions. The primary transcript forms one or several bulging double stranded …

The microRNAs (miRNAs) are a class of small, 20–22 nucleotides in length, endogenously
expressed noncoding RNAs that regulate multiple targets posttranscriptionally. Interestingly …

Metastatic lung cancer is one of the most lethal forms of cancer and molecular pathways
driving metastasis are still not clearly elucidated. Metastatic cancer cells undergo an …

Background hTERT gene plays an important role in melanoma, although the specific
mechanism involved is unclear. The aim of this study was to screen and identify the relative …

Objective MicroRNAs (miRNAs) are well-known regulators of disease pathogenesis and
have great potential as biomarkers and therapeutic targets. We aimed at profiling miRNAs in …

Cancer remains a worldwide epidemic. An improved understanding of the underlying
molecular mechanisms and development of effective targeted therapies are still required for …

Gene expression is in part regulated by microRNAs (miRNAs). This review summarizes the
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …

Several microRNAs (miRNAs) are known to be deregulated in colon cancer, but the
mechanisms behind their potential involvement on proliferation and tumor cell survival are …