Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice

M Ząbczyk, RAS Ariëns, A Undas - Cardiovascular research, 2023 - academic.oup.com
Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

The prothrombotic state in atrial fibrillation: pathophysiological and management implications

AA Khan, GYH Lip - Cardiovascular research, 2019 - academic.oup.com
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is associated with
significant morbidity and mortality. There is plenty of evidence available to support the …

Prothrombotic fibrin clot properties associated with NETs formation characterize acute pulmonary embolism patients with higher mortality risk

M Ząbczyk, J Natorska, A Janion-Sadowska… - Scientific Reports, 2020 - nature.com
Venous thromboembolism is associated with formation of denser fibrin clots resistant to lysis.
We investigated whether prothrombotic plasma clot properties are associated with the …

Thromboembolism and bleeding in patients with atrial fibrillation and stage 4 chronic kidney disease: impact of biomarkers

PT Matusik, WJ Leśniak, Z Heleniak… - … Polska (Polish Heart …, 2021 - journals.viamedica.pl
Background: Chronic kidney disease (CKD) is considered a risk factor for thromboembolic
and bleeding events in patients with atrial fibrillation (AF). Aims: We sought to assess …

[HTML][HTML] Coagulation factors and fibrinolytic activity in the left atrial appendage and other heart chambers in patients with atrial fibrillation: is there a local intracardiac …

K Bartus, R Litwinowicz, J Natorska, M Zabczyk… - International Journal of …, 2020 - Elsevier
Introduction Atrial fibrillation (AF), a risk factor for stroke and systemic thromboembolism, is
associated with unfavorable fibrin clot properties and increased thrombus formation in …

Heart rate variability in patients with systemic lupus erythematosus: a systematic review and methodological considerations

PS Matusik, PT Matusik, PK Stein - Lupus, 2018 - journals.sagepub.com
Aim The aim of this review was to summarize current knowledge about the scientific findings
and potential clinical utility of heart rate variability measures in patients with systemic lupus …

Association of NT-proBNP and GDF-15 with markers of a prothrombotic state in patients with atrial fibrillation off anticoagulation

PT Matusik, B Małecka, J Lelakowski… - Clinical Research in …, 2020 - Springer
We investigated whether growth differentiation factor-15 (GDF-15), also known as
macrophage inhibitory cytokine-1 (MIC-1), levels are associated with a prothrombotic state …

Presence of retained calcified fibrin sheath after central venous catheter removal: A systematic literature review

PS Matusik, P Łoboda, K Krzanowska… - The Journal of …, 2022 - journals.sagepub.com
Central venous catheters (CVC) are used in many clinical settings for a variety of indications.
We performed a systematic literature review concerning case reports of retained calcified …

Neutrophil-activating peptide 2 as a novel modulator of fibrin clot properties in patients with atrial fibrillation

M Ząbczyk, J Natorska, PT Matusik, P Mołek… - Translational Stroke …, 2024 - Springer
Abstract Neutrophil-activating peptide 2 (NAP-2, CXCL7), a platelet-derived neutrophil
chemoattractant, is involved in inflammation. We investigated associations between NAP-2 …

Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state

K Nowak, M Zabczyk, J Natorska, J Zalewski… - Journal of Thrombosis …, 2024 - Springer
Introduction Plasma protein carbonylation that reflects oxidative stress has been
demonstrated to be associated with the prothrombotic fibrin clot phenotype. However, the …