Inflammation is an important homeostatic mechanism that limits the effects of infectious
agents. However, inflammation might be self-damaging and therefore has to be tightly …

Giant cell arteritis is the most common large vessel vasculitis. Classic symptoms include
headaches, scalp tenderness, visual loss and muscle stiffness and pain. First line treatment …

OBJECTIVE: This study sought to characterize the inflammatory infiltrate in ascending
thoracic aortic aneurysm in patients with Marfan syndrome, familial thoracic aortic aneurysm …

Objectives: The aim of this study was to assess the influence of pro-inflammatory interleukin
(IL)-1 genotype status on the risk for coronary artery disease (CAD), defined as> 50 …

Giant cell arteritis (GCA) is characterized by intimal hyperplasia and luminal obstruction
leading to ischemic manifestations involving extra-cranial branches of carotid arteries and …

Glucocorticoids remain the cornerstone of medical therapy in giant cell arteritis (GCA) and
should be started immediately to prevent severe consequences of the disease, such as …

Giant cell arteritis is a primary large-vessel vasculitis characterized by an arterial wall
inflammation associated with intimal hyperplasia leading to arterial occlusion …

Background Deficiency of interleukin 1 receptor antagonist (DIRA) is a recently described
autoinflammatory syndrome of skin and bone caused by recessive mutations in the gene …

Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are the two main large vessel
vasculitides. They share some similarities regarding their clinical, radiological and …

Monogenic autoinflammatory syndromes are a rare group of disorders characterized by
periodic episodes of systemic inflammation of endogenous origin. Sometimes, these …