The genetic and environmental factors for keratoconus

A Gordon-Shaag, M Millodot… - BioMed research …, 2015 - Wiley Online Library
Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone‐
shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It …

Molecular and histopathological changes associated with keratoconus

ML Khaled, I Helwa, M Drewry… - BioMed research …, 2017 - Wiley Online Library
Keratoconus (KC) is a corneal thinning disorder that leads to loss of visual acuity through
ectasia, opacity, and irregular astigmatism. It is one of the leading indicators for corneal …

The cascade hypothesis of keratoconus

MC Kenney, DJ Brown - Contact lens and anterior eye, 2003 - Elsevier
Keratoconus, a non-inflammatory thinning of the cornea, is a leading indication for corneal
transplantation. For its causation, we propose a “Cascade Hypothesis” stating that …

The genetics of keratoconus

M Edwards, CNJ McGhee… - Clinical & experimental …, 2001 - Wiley Online Library
Keratoconus is a relatively common, bilateral, non‐inflammatory corneal ectasia. The
aetiology of this condition is probably multifactorial, or it represents the final common …

The genetics of keratoconus.

YS Rabinowitz - Ophthalmology Clinics of North America, 2003 - europepmc.org
The genetics of keratoconus. - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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[HTML][HTML] Review and update on the molecular basis of Leber congenital amaurosis

OF Chacon-Camacho, JC Zenteno - World Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Inherited retinal diseases are uncommon pathologies and one of the most harmful causes of
childhood and adult blindness. Leber congenital amaurosis (LCA) is the most severe kind of …

Pediatric keratoconus-Current perspectives and clinical challenges

V Anitha, M Vanathi, A Raghavan… - Indian Journal of …, 2021 - journals.lww.com
Keratoconus is an ectatic corneal disease characterized by progressive stromal thinning,
irregular astigmatism, and defective vision. It can be unilateral or bilateral with asymmetric …

Trophic factors in the pathogenesis and therapy for retinal degenerative diseases

AM Kolomeyer, MA Zarbin - Survey of ophthalmology, 2014 - Elsevier
Trophic factors are endogenously secreted proteins that act in an autocrine and/or paracrine
fashion to affect vital cellular processes such as proliferation, differentiation, and …

keratoconus in Asia

YO Kok, GFL Tan, SC Loon - Cornea, 2012 - journals.lww.com
Keratoconus is an ectatic corneal disorder for which exciting therapeutic and diagnostic
technologies are emerging. However, its pathogenesis is still heterogeneous and elusive …

Genetic and environmental risk factors for keratoconus

SEM Lucas, KP Burdon - Annual Review of Vision Science, 2020 - annualreviews.org
Keratoconus, a progressive corneal ectasia, is a complex disease with both genetic and
environmental risk factors. The exact etiology is not known and is likely variable between …