Heparin-induced thrombocytopenia in cardiac surgery and critically ill patients

S Selleng, K Selleng - Thrombosis and Haemostasis, 2016 - thieme-connect.com
Thrombocytopenia as well as anti-platelet factor 4/heparin (PF4/H) antibodies are common
in cardiac surgery patients and those treated in the intensive care unit. In contrast, heparin …

Superior outcomes with Argatroban for heparin-induced thrombocytopenia: a Bayesian network meta-analysis

G Colarossi, N Maffulli, A Trivellas, H Schnöring… - International Journal of …, 2021 - Springer
Background Argatroban, lepirudin, desirudin, bivalirudin, and danaparoid are commonly
used to manage heparin-induced thrombocytopenia related complications. However, the …

Comparisons of argatroban to lepirudin and bivalirudin in the treatment of heparin-induced thrombocytopenia: a systematic review and meta-analysis

Z Sun, X Lan, S Li, H Zhao, Z Tang, Y Xi - International journal of …, 2017 - Springer
To prevent thromboembolic events associated with heparin-induced thrombocytopenia
(HIT), patients usually are treated with argatroban, lepirudin, and bivalirudin. Here, we …

Update on argatroban for the prophylaxis and treatment of heparin-induced thrombocytopenia type II

E Grouzi - Journal of Blood Medicine, 2014 - Taylor & Francis
Heparin-induced thrombocytopenia (HIT) is a rare but potentially severe complication of
heparin therapy that is strongly associated with venous and arterial thrombosis (HIT and …

Argatroban in heparin-induced thrombocytopenia: rationale for use and place in therapy

RK Bambrah, DC Pham, F Rana - Therapeutic advances in …, 2013 - journals.sagepub.com
Heparin-induced thrombocytopenia (HIT) is a recognized complication of heparin and
requires urgent detection and treatment. HIT can be divided into two types, type I and type II …

[PDF][PDF] 水蛭素的药理作用及临床应用研究进展

徐明杰, 赵迪, 李龙宇, 伍一炜, 徐暾海, 刘铜华 - 中国现代中药, 2021 - jkdf1913.cn
水蛭素(hirudin) 为特异性凝血酶抑制剂, 根据其来源可分为天然水蛭素和重组水蛭素两类.
水蛭素具有抗凝, 抗血栓, 抗纤维化, 抗细胞凋亡, 舒血管和提高随意皮瓣成活率等多种药理作用 …

Prognostic factors for patients with heparin-induced thrombocytopenia: a systematic review

G Colarossi, H Schnoering, A Trivellas… - International Journal of …, 2021 - Springer
Background Little is known with regards to the prognostic factors for patients with suspected
or diagnosed Heparin-Induced Thromobocytopenia (HIT). The role of patient and therapy …

Argatroban for heparin-induced thrombocytopenia during venovenous extracorporeal membrane oxygenation with continuous venovenous hemofiltration

JH Sin, ND Lopez - The Journal of ExtraCorporeal …, 2017 - ject.edpsciences.org
Patients receiving extracorporeal membrane oxygenation (ECMO) are at risk of circuit
thrombosis due to constant contact between blood and the extracorporeal components …

[PDF][PDF] 阿加曲班在肾脏替代治疗中应用的Meta 分析

曹芳芳, 张海涛, 冯雪, 焦若男 - 中国医学科学院 …, 2013 - journal13.magtechjournal.com
目的评价直接凝血酶抑制剂阿加曲班在肾脏替代治疗中应用的作用效果.
方法以“阿加曲班”,“透析”,“肾功能”,“肾功能衰竭”,“肾脏替代治疗” 为关键词, 在Cochrane 图书馆 …

比伐卢定序贯给药在中国健康受试者中的药代, 药效及安全性研究

柴栋, 王睿, 白楠, 梅和坤 - 中国临床药理学与治疗学, 2014 - manu41.magtech.com.cn
目的探讨合理的比伐卢定临床序贯给药方案. 方法筛选健康受试者12 名, 给予比伐卢定0.75
mg/kg 静脉推注后, 1.75 mg· kg-1· h-1 的速度匀速静滴4 h, 不同时间点采集血样, 测定血药浓度 …