The quest to find milder and more sustainable methods to generate highly reactive, carbon-
centred intermediates has led to a resurgence of interest in radical chemistry. In particular …

Advances in nickel-catalyzed cross-coupling reactions have expanded the chemical space
of accessible structures and enabled new synthetic disconnections. The unique properties of …

Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to
join two electrophiles. These reactions have proven particularly useful for the coupling of sec …

The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters)
and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …

Cross-electrophile coupling (XEC), defined by us as the cross-coupling of two different σ-
electrophiles that is driven by catalyst reduction, has seen rapid progression in recent years …

Over the past decade, bicyclo [1.1. 1] pentane (BCP) motifs have come to the fore as
valuable pharmaceutical bioisosteres of para-disubstituted benzenes. However, the limited …

Transformation of sterically hindered tertiary alkyl electrophiles under nickel-catalyzed
conditions to forge C (sp3)–C bonds and simultaneously create challenging all-carbon …

The merger of photoredox and transition-metal catalysis has evolved as a robust platform in
organic synthesis over the past decade. The stereoselective 1, 4-functionalization of 1, 3 …

The concept of reductive radical-polar crossover (RRPCO) reactions has recently emerged
as a valuable and powerful tool to overcome limitations of both radical and traditional polar …

As a key element in the construction of complex organic scaffolds, the formation of C− C
bonds remains a challenge in the field of synthetic organic chemistry. Recent advancements …