The firm integration of anterior cruciate ligament (ACL) grafts into bones remains the most
demanding challenge in ACL reconstruction, since graft loosening means graft failure. For a …

Identifying constitutive parameters in engineering and biological materials, particularly those
with intricate geometries and mechanical behaviors, remains a longstanding challenge. The …

We present a novel, fully three-dimensional approach to soft material characterization and
constitutive modeling with relevance to soft biological tissue. Our approach leverages recent …

Recently, various machine learning methods have been developed to model the stress-
strain constitutive behavior of materials. In these methods, a large database of multi-axial …

It is of great significance to identify the nonhomogeneous distribution of material properties
in human tissues for different clinical and medical applications. This leads to the requirement …

Identifying constitutive parameters in engineering and biological materials, particularly those
with intricate geometries and mechanical behaviors, remains a longstanding challenge. The …

Degenerative diseases such as osteoarthritis (OA) result in deterioration of cartilage
extracellular matrix (ECM) components, significantly compromising tissue function. For …

Soft tissue injuries (such as ligament, tendon, and meniscus tears) are the result of
extracellular matrix damage from excessive tissue stretching. Deformation thresholds for soft …

Fiber networks underlie the mechanical behavior of a wide range of natural and engineered
materials. Interestingly, these networks are often embedded within amorphous matrices …

Contemporary material characterization techniques that leverage deformation fields and the
weak form of the equilibrium equations face challenges in the numerical solution procedure …