Degenerate neuronal and circuit mechanisms important for generating rhythmic motor patterns
RL Calabrese, E Marder - Physiological reviews, 2025 - journals.physiology.org
In 1996, we published a review article (Marder E, Calabrese RL. Physiol Rev 76: 687–717,
1996) describing the state of knowledge about the structure and function of the central …
1996) describing the state of knowledge about the structure and function of the central …
Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output
Extracellular potassium concentration ([K+] e) is known to increase as a function of
arousal.[K+] e is also a potent modulator of transmitter release. Yet, it is not known whether …
arousal.[K+] e is also a potent modulator of transmitter release. Yet, it is not known whether …
The Brain's Best Kept Secret Is Its Degenerate Structure
Degeneracy is defined as multiple sets of solutions that can produce very similar system
performance. Degeneracy is seen across phylogenetic scales, in all kinds of organisms. In …
performance. Degeneracy is seen across phylogenetic scales, in all kinds of organisms. In …
Gating of homeostatic regulation of intrinsic excitability produces cryptic long-term storage of prior perturbations
Neurons and neuronal circuits must maintain their function throughout the life of the
organism despite changing environments. Previous theoretical and experimental work …
organism despite changing environments. Previous theoretical and experimental work …
Individual variability, statistics, and the resilience of nervous systems of crabs and humans to temperature and other perturbations
E Marder - Eneuro, 2023 - eneuro.org
Every so often, I conclude that life is not possible. It is not uncommon for me to walk out of a
seminar about the pathways and dynamics of biochemical signaling or the structure of …
seminar about the pathways and dynamics of biochemical signaling or the structure of …
Intrinsic adaptive plasticity in mouse and human sensory neurons
LA McIlvried, JS Del Rosario, MY Pullen… - Journal of General …, 2025 - rupress.org
In response to changes in activity induced by environmental cues, neurons in the central
nervous system undergo homeostatic plasticity to sustain overall network function during …
nervous system undergo homeostatic plasticity to sustain overall network function during …
Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures
SE Saunders, JM Santin - BMC biology, 2024 - Springer
Background Neural circuits produce reliable activity patterns despite disturbances in the
environment. For this to occur, neurons elicit synaptic plasticity during perturbations …
environment. For this to occur, neurons elicit synaptic plasticity during perturbations …
[HTML][HTML] Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons
In response to changes in activity induced by environmental cues, neurons in the central
nervous system undergo homeostatic plasticity to sustain overall network function during …
nervous system undergo homeostatic plasticity to sustain overall network function during …
Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures
SE Saunders, JM Santin - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Background: Neural circuits produce reliable activity patterns despite disturbances in the
environment. For this to occur, neurons elicit synaptic plasticity during perturbations …
environment. For this to occur, neurons elicit synaptic plasticity during perturbations …