Management and investigation of neonatal encephalopathy: 2017 update

K Martinello, AR Hart, S Yap, S Mitra… - Archives of Disease in …, 2017 - fn.bmj.com
This review discusses an approach to determining the cause of neonatal encephalopathy,
as well as current evidence on resuscitation and subsequent management of hypoxic …

Getting an early start in understanding perinatal asphyxia impact on the cardiovascular system

MR Popescu, AM Panaitescu, B Pavel… - Frontiers in …, 2020 - frontiersin.org
Perinatal asphyxia (PA) is a burdening pathology with high short-term mortality and severe
long-term consequences. Its incidence, reaching as high as 10 cases per 1000 live births in …

Maternal obesity and risk of cardiovascular diseases in offspring: a population-based cohort and sibling-controlled study

N Razaz, E Villamor, GM Muraca… - The lancet Diabetes & …, 2020 - thelancet.com
Background Maternal overweight and obesity might increase risks of adiposity and
cardiovascular and metabolic diseases in offspring. We examined associations between …

Hemodynamic instability in the critically ill neonate: an approach to cardiovascular support based on disease pathophysiology

RE Giesinger, PJ McNamara - Seminars in perinatology, 2016 - Elsevier
Hemodynamic disturbance in the sick neonate is common, highly diverse in underlying
pathophysiology and dynamic. Dysregulated systemic and cerebral blood flow is …

[HTML][HTML] Neonatal multiple organ failure after perinatal asphyxia

I Iribarren, E Hilario, A Álvarez… - Anales de Pediatría …, 2022 - Elsevier
Perinatal asphyxia is an event with far-reaching consequences that can lead not only to the
development of neonatal encephalopathy, but also to multiple organ failure (MOF). This …

Impaired right ventricular performance is associated with adverse outcome after hypoxic ischemic encephalopathy

RE Giesinger, AI El Shahed, MP Castaldo… - American journal of …, 2019 - atsjournals.org
Rationale: Asphyxiated neonates with hypoxic ischemic encephalopathy (HIE) are at risk of
myocardial dysfunction; however, echocardiography studies are limited and little is known …

Management of multi organ dysfunction in neonatal encephalopathy

M O'Dea, D Sweetman, SL Bonifacio, M El-Dib… - Frontiers in …, 2020 - frontiersin.org
Neonatal Encephalopathy (NE) describes neonates with disturbed neurological function in
the first post-natal days of life. NE is an overall term that does not specify the etiology of the …

Hypoxic-ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective

RE Giesinger, LJ Bailey, P Deshpande… - The Journal of …, 2017 - jpeds.com
Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in
neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive …

Neonatal encephalopathy with group B streptococcal disease worldwide: systematic review, investigator group datasets, and meta-analysis

CJ Tann, KA Martinello, S Sadoo… - Clinical Infectious …, 2017 - academic.oup.com
Background Neonatal encephalopathy (NE) is a leading cause of child mortality and longer-
term impairment. Infection can sensitize the newborn brain to injury; however, the role of …

Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy

KA Martinello, C Meehan, A Avdic-Belltheus… - Scientific Reports, 2019 - nature.com
Co-existing infection/inflammation and birth asphyxia potentiate the risk of developing
neonatal encephalopathy (NE) and adverse outcome. In a newborn piglet model we …