Background falls and fall-related injuries are common in older adults, have negative effects
on functional independence and quality of life and are associated with increased morbidity …

The concept of 'idiopathic'Parkinson's disease (PD) as a single entity has been challenged
with the identification of several clinical subtypes, pathogenic genes and putative causative …

In patients with Parkinson's disease, heterogeneous cholinergic system changes can occur
in different brain regions. These changes correlate with a range of clinical features, both …

Gait impairments are among the most common and disabling symptoms of Parkinson's
disease. Nonetheless, gait is not routinely assessed quantitatively but is described in …

Objective: The objective of this review was to update evidence‐based medicine
recommendations for treating motor symptoms of Parkinson's disease (PD). Background …

Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …

Background: Parkinson's disease (PD) is a common and disabling pathology that is
characterized by both motor and non-motor symptoms and affects millions of people …

Parkinson disease (PD) treatment options have conventionally focused on dopamine
replacement and provision of symptomatic relief. Current treatments cause undesirable …

Distinct gait characteristics like short steps and shuffling gait are prototypical signs
commonly observed in Parkinson's disease. Routinely assessed by observation through …

Falls are a major determinant of poor quality of life, immobilization, and reduced life
expectancy in people affected by Parkinson's disease (PD) and in older adults more …