Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system

WT Chan, MP Garcillán-Barcia, CC Yeo… - FEMS Microbiology …, 2023 - academic.oup.com
Toxin–antitoxin (TA) systems are entities found in the prokaryotic genomes, with eight
reported types. Type II, the best characterized, is comprised of two genes organized as an …

Bacterial toxin-antitoxin systems' cross-interactions—implications for practical use in medicine and biotechnology

L Boss, B Kędzierska - Toxins, 2023 - mdpi.com
Toxin-antitoxin (TA) systems are widely present in bacterial genomes. They consist of stable
toxins and unstable antitoxins that are classified into distinct groups based on their structure …

Identification of a 301 bp promoter core region of the SrUGT91D2 gene from Stevia rebaudiana that contributes to hormone and abiotic stress inducibility

J Chen, R Liu, C Lyv, M Wu, S Liu, M Jiang, Y Zhang… - BMC Plant …, 2024 - Springer
Abstract Background The UDP-glucuronosyltransferase 91D2 (SrUGT91D2) gene is a
crucial element in the biosynthetic pathway of steviol glycosides (SGs) and is responsible for …

Interactions of the Streptococcus pneumoniae Toxin-Antitoxin RelBE Proteins with Their Target DNA

I Moreno-Córdoba, WT Chan, C Nieto, M Espinosa - Microorganisms, 2021 - mdpi.com
Type II bacterial toxin-antitoxin (TA) systems are found in most bacteria, archaea, and mobile
genetic elements. TAs are usually found as a bi-cistronic operon composed of an unstable …

Minigene as a novel regulatory element in toxin-antitoxin systems

B Kędzierska, K Potrykus - International Journal of Molecular Sciences, 2021 - mdpi.com
The axe-txe type II toxin-antitoxin (TA) system is characterized by a complex and
multilayered mode of gene expression regulation. Precise and tight control of this process is …