Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity. Cytokine receptors transduce important signals …
ETTL Tjwa, GW van Oord, JP Hegmans… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Natural killer (NK) cells play a major role in anti-viral immunity as first line defense and regulation of virus-specific T cell responses. This study aimed to …
Natural killer (NK) cells were first described as immune leukocytes that could kill tumor cells and soon after were reported to kill virus-infected cells. In the mid-1980s, 10 years after their …
CN Baxevanis, SA Perez… - Critical reviews in clinical …, 2009 - Taylor & Francis
Recent scientific advances have expanded our understanding of the immune system and its response to malignant cells. The clinical goal of tumour immunotherapy is to provide either …
M Donia, N Junker, E Ellebaek… - Scandinavian …, 2012 - Wiley Online Library
Adoptive cell therapy (ACT) with ex vivo expanded tumour‐infiltrating lymphocytes (TILs) in combination with IL‐2 is an effective treatment for metastatic melanoma. Modified protocols …
Background Natural killer (NK) cells are critical innate effector cells whose development is dependent on the Janus kinase–signal transducer and activator of transcription (STAT) …
Natural killer (NK) cells are innate lymphoid cells (ILC) known for their ability to recognize and rapidly eliminate infected or transformed cells. Consequently, NK cells are fundamental …
VI Seledtsov, AG Goncharov… - Human vaccines & …, 2015 - Taylor & Francis
The immune system exerts both tumor-destructive and tumor-protective functions. Mature dendritic cells (DCs), classically activated macrophages (M1), granulocytes, B lymphocytes …
E Dounousi, A Duni, KK Naka… - Current Vascular …, 2021 - ingentaconnect.com
Adverse innate immune responses have been implicated in several disease processes, including cardiovascular disease (CVD) and chronic kidney disease (CKD). The monocyte …