The sex-dependent response to psychosocial stress and ischaemic heart disease

TJ Helman, JP Headrick, NJC Stapelberg… - Frontiers in …, 2023 - frontiersin.org
Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

Chronic nicotine exposure alters sperm small RNA content in C57BL/6J mouse model

D Zeid, TJ Gould - Developmental psychobiology, 2023 - Wiley Online Library
Multigenerational inheritance is a nongenomic form of heritability characterized by altered
phenotypes in the first generation born from the exposed parent. Multigenerational factors …

Sex-biased gene and microRNA expression in the developing mouse brain is associated with neurodevelopmental functions and neurological phenotypes

S Szakats, A McAtamney, H Cross, MJ Wilson - Biology of sex Differences, 2023 - Springer
Background Sex differences pose a challenge and an opportunity in biomedical research.
Understanding how sex chromosomes and hormones affect disease-causing mechanisms …

Baicalin ameliorates corticosterone-induced depression by promoting neurodevelopment of hippocampal via mTOR/GSK3β pathway

Z Wang, Y Cheng, Y Lu, G Sun, L Pei - Chinese journal of integrative …, 2023 - Springer
Objective To investigate the role of hippocampal neurodevelopment in the antidepressant
effect of baicalin. Methods Forty male Institute of Cancer Research mice were divided into …

Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons

D You, JD Cohen, O Pustovalova, L Lewis… - Toxicological …, 2022 - academic.oup.com
Elucidation of predictive fluidic biochemical markers to detect and monitor chemical-induced
neurodegeneration has been a major challenge due to a lack of understanding of molecular …

[HTML][HTML] Baicalin coadministration with lithium chloride enhanced neurogenesis via GSK3β pathway in corticosterone induced PC-12 cells

Z Wang, Y Cheng, Y Lu, G Sun, L Pei - … and Pharmaceutical Bulletin, 2022 - jstage.jst.go.jp
Accumulating studies suggest that hippocampal neurogenesis plays a crucial role in the
pathological mechanism of depression. As a classic antidepressant, lithium chloride can …

Chronic nicotine exposure alters sperm small RNA content in a C57BL/6J mouse model: Implications for multigenerational inheritance

D Zeid, TJ Gould - bioRxiv, 2022 - biorxiv.org
Multigenerational inheritance is a non-genomic form of heritability characterized by altered
phenotypes in the first generation born from the exposed parent. Multigenerational factors …

[PDF][PDF] Sex, Brains & RNA: Origins of sex-biased gene and microRNA expression in the developing mouse brain

SK Szakats - 2022 - ourarchive.otago.ac.nz
Sex differences pose a challenge and an opportunity in biomedical research. Existing data
is primarily derived from studies that fail to include female subjects and/or fail to stratify …