Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Abstract The NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome is
an immunological sensor that detects a wide range of microbial-and host-derived signals …

The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain
containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns …

In the elderly, systemic infection is associated with an increased frequency of behavioral and
cognitive complications. We have reported that peripheral stimulation of the innate immune …

Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Cellular senescence is a proliferation arrest that is typically irreversible and caused by
various cellular stresses, including excess rounds of cell division and cancer-causing …

Inflammasomes are important in human health and disease, whereby they control the
secretion of IL-1β and IL-18, two potent proinflammatory cytokines that play a key role in …

Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …

Apoptosis is a crucial program of cell death that controls development and homeostasis of
multicellular organisms. The main initiators and executors of this process are the Cysteine …