An important goal of biomedical research is to translate basic research findings into useful
medical advances. In the field of neuropharmacology this requires understanding disease …

Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

Background: Despite positive preclinical studies and two positive Phase II clinical trials, two
large Phase III clinical trials of progesterone treatment of acute traumatic brain injury (TBI) …

The ischemic penumbra defined four decades ago has been the main battleground of
ischemic stroke. The evolving ischemic penumbra concept has been providing insight for the …

Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss
of blood flow to a brain region due to an ischemic insult leads to severe damage to that area …

This meta-analysis combines the results of nine ischemic stroke trials, assessing efficacy of
Cerebrolysin on global neurological improvement during early post-stroke period …

The constant failure of new neuroprotective therapies for ischemic stroke has partially halted
the search for new therapies in recent years, mainly because of the high investment risk …

Currently, the recovery of cognitive function has become an essential part of stroke
rehabilitation. DL-3-n-butylphthalide (NBP) is a neuroprotective reagent and has been used …

Thrombolysis and mechanical thrombectomy have revolutionized the care of patients with
acute ischemic stroke. The number of patients who can benefit from these treatments …

Background Dysregulated activation of the inflammasome is involved in various human
diseases including acute cerebral ischemia, multiple sclerosis and sepsis. Though many …