Exosome engineering in cell therapy and drug delivery

S Sadeghi, FR Tehrani, S Tahmasebi, A Shafiee… - …, 2023 - Springer
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

Re-engineering extracellular vesicles as smart nanoscale therapeutics

JPK Armstrong, MN Holme, MM Stevens - ACS nano, 2017 - ACS Publications
In the past decade, extracellular vesicles (EVs) have emerged as a key cell-free strategy for
the treatment of a range of pathologies, including cancer, myocardial infarction, and …

Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …

Recent trends in preparation and biomedical applications of iron oxide nanoparticles

YQ Meng, YN Shi, YP Zhu, YQ Liu, LW Gu… - Journal of …, 2024 - Springer
The iron oxide nanoparticles (IONPs), possessing both magnetic behavior and
semiconductor property, have been extensively used in multifunctional biomedical fields due …

Engineered extracellular vesicles: tailored-made nanomaterials for medical applications

K Man, MY Brunet, MC Jones, SC Cox - Nanomaterials, 2020 - mdpi.com
Extracellular vesicles (EVs) are emerging as promising nanoscale therapeutics due to their
intrinsic role as mediators of intercellular communication, regulating tissue development and …

Assembling living building blocks to engineer complex tissues

L Ouyang, JPK Armstrong… - Advanced Functional …, 2020 - Wiley Online Library
The great demand for tissue and organ grafts, compounded by an aging demographic and a
shortage of available donors, has driven the development of bioengineering approaches …

Using remote fields for complex tissue engineering

JPK Armstrong, MM Stevens - Trends in biotechnology, 2020 - cell.com
Great strides have been taken towards the in vitro engineering of clinically relevant tissue
constructs using the classic triad of cells, materials, and biochemical factors. In this …

In Situ One-Pot Synthesis of Fe2O3@BSA Core-Shell Nanoparticles as Enhanced T1-Weighted Magnetic Resonance Imagine Contrast Agents

S Xu, J Wang, Y Wei, H Zhao, T Tao… - … Applied Materials & …, 2020 - ACS Publications
Ultra-small-sized iron oxide nanoparticles with good biocompatibility are regarded as
promising alternatives for the gadolinium-based contrast agents, which are widely used as a …

Efficient encapsulation of biocompatible nanoparticles in exosomes for cancer theranostics

T Tanziela, S Shaikh, H Jiang, Z Lu, X Wang - Nano Today, 2020 - Elsevier
Exosomes secrete from various cells and can be separated from all biological fluids, which
possess the properties of their origin, and function as cell communication. Moreover, the …

Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation

B Chen, J Sun, F Fan, X Zhang, Z Qin, P Wang, Y Li… - Nanoscale, 2018 - pubs.rsc.org
Ferumoxytol, which is originally intended for MRI and anemia treatment, is currently the only
inorganic nanodrug approved by FDA for clinical application in vivo. Common ferumoxytol …