Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Type I interferons (IFN-I) were first discovered as an antiviral factor by Isaacs and
Lindenmann in 1957, but they are now known to also modulate innate and adaptive …

Human papillomavirus (HPV) is a necessary but insufficient cause of a subset of oral
squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify …

IFNs are comprised of three families of cytokines that confer protection against pathogen
infection and uncontrolled cellular proliferation. The broad role IFNs play in innate and …

Human papillomaviruses (HPV) are the causative agents of the most common sexually
transmitted infection worldwide. While infection is generally asymptomatic and can be …

Human papillomaviruses (HPVs) infect keratinocytes of stratified epithelia. Long-term
persistence of infection is a critical risk factor for the development of HPV-induced …

Interferons (IFNs) are a group of signaling cytokines, secreted by host cells to induce
protection against various disorders. IFNs can directly impact on tumor cells or indirectly …

High-risk human papillomaviruses (HR HPVs) are associated with multiple human cancers
and comprise 5% of the human cancer burden. Although most infections are transient …

Regulation of human papillomavirus (HPV) gene expression is tightly linked to differentiation
of the keratinocytes the virus infects. HPV late gene expression is confined to the cells in the …

Human papillomavirus (HPV) contributes to sexually transmitted infection, which is primarily
associated with pre-cancerous and cancerous lesions in both men and women and is …