Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …

Similar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs
have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (m6A) …

In the physiological condition, the skeletal system's bone resorption and formation are in
dynamic balance, called bone homeostasis. However, bone homeostasis is destroyed under …

Background Osteoblast differentiation is a vital process for fracture healing, and exosomes
are nanosized membrane vesicles that can deliver therapeutic drugs easily and safely …

Abstract N6-methyladenosine (m6A) is the most prevalent RNA modification at the
posttranscriptional level and involved in various diseases and cellular processes. However …

Impaired osteoblast function is involved in osteoporosis, and microRNA (miRNA)
dysregulation may cause abnormal osteoblast osteogenic activity. However, the influence of …

Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

Background Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-
renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial …

Osteoporosis is a systemic metabolic disease, mainly characterized by reduced bone
mineral density and destruction of bone tissue microstructure. However, the molecular …

With the aging of the global population, accumulating interest is focused on manipulating the
fundamental aging‐related signaling pathways to delay the physiological aging process and …