Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

YQ He, CC Zhou, LY Yu, L Wang, J Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …

Reappraisal of ventilator-free days in critical care research

N Yehya, MO Harhay, MAQ Curley… - American journal of …, 2019 - atsjournals.org
Ventilator-free days (VFDs) are a commonly reported composite outcome measure in acute
respiratory distress syndrome trials. VFDs combine survival and duration of ventilation in a …

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus… - Intensive care …, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

Phenotypes and personalized medicine in the acute respiratory distress syndrome

MA Matthay, YM Arabi, ER Siegel, LB Ware… - Intensive care …, 2020 - Springer
Although the acute respiratory distress syndrome (ARDS) is well defined by the
development of acute hypoxemia, bilateral infiltrates and non-cardiogenic pulmonary …

ARDS clinical practice guideline 2021

S Tasaka, S Ohshimo, M Takeuchi, H Yasuda… - Journal of intensive …, 2022 - Springer
Background The joint committee of the Japanese Society of Intensive Care
Medicine/Japanese Respiratory Society/Japanese Society of Respiratory Care Medicine on …

Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Clinical manifestations and outcomes of critically ill children and adolescents with coronavirus disease 2019 in New York City

KR Derespina, S Kaushik, A Plichta… - The Journal of …, 2020 - Elsevier
Objectives To describe the clinical manifestations and outcomes of critically ill children with
coronavirus disease-19 (COVID-19) in New York City. Study design Retrospective …

Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis

MK Dahmer, G Yang, M Zhang… - The Lancet …, 2022 - thelancet.com
Background Previous latent class analysis of adults with acute respiratory distress syndrome
(ARDS) identified two phenotypes, distinguished by the degree of inflammation. We aimed …

Why COVID-19 is less frequent and severe in children: a narrative review

R Sinaei, S Pezeshki, S Parvaresh, R Sinaei - World Journal of Pediatrics, 2021 - Springer
Background Despite the streaks of severity, severe acute respiratory syndrome-coronavirus-
2 (SARS-CoV-2) infection is, in general, less frequent and severe in children than in adults …

Single cell transcriptomics identifies distinct profiles in pediatric acute respiratory distress syndrome

T Flerlage, JC Crawford, EK Allen, D Severns… - Nature …, 2023 - nature.com
Acute respiratory distress syndrome (ARDS), termed pediatric ARDS (pARDS) in children, is
a severe form of acute respiratory failure (ARF). Pathologic immune responses are …