Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Blood flow restriction exercise: considerations of methodology, application, and safety

SD Patterson, L Hughes, S Warmington, J Burr… - Frontiers in …, 2019 - frontiersin.org
The current manuscript sets out a series of guidelines for blood flow restriction exercise,
focusing on the methodology, application and safety of this mode of training. With the …

Resistance training recommendations to maximize muscle hypertrophy in an athletic population: Position stand of the IUSCA

B Schoenfeld, J Fisher, J Grgic, C Haun… - … Journal of Strength …, 2021 - journal.iusca.org
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of
a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle …

[HTML][HTML] Loading recommendations for muscle strength, hypertrophy, and local endurance: a re-examination of the repetition continuum

BJ Schoenfeld, J Grgic, DW Van Every, DL Plotkin - Sports, 2021 - mdpi.com
Sports | Free Full-Text | Loading Recommendations for Muscle Strength, Hypertrophy, and
Local Endurance: A Re-Examination of the Repetition Continuum Next Article in Journal …

[HTML][HTML] An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy

C Lim, EA Nunes, BS Currier, JC Mcleod… - Medicine and science …, 2022 - ncbi.nlm.nih.gov
Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …

[HTML][HTML] Blood flow restriction therapy and its use for rehabilitation and return to sport: physiology, application, and guidelines for implementation

DJ Cognetti, AJ Sheean, JG Owens - Arthroscopy, sports medicine, and …, 2022 - Elsevier
Blood flow restriction (BFR) is an expanding rehabilitation modality that uses a tourniquet to
reduce arterial inflow and occlude venous outflow in the setting of resistance training or …

The evolution of blood flow restricted exercise

EDS Freitas, M Karabulut, MG Bemben - Frontiers in physiology, 2021 - frontiersin.org
The use of blood flow restricted (BFR) exercise has become an accepted alternative
approach to improve skeletal muscle mass and function and improve cardiovascular …

Role of macrophages during skeletal muscle regeneration and hypertrophy—Implications for immunomodulatory strategies

C Bernard, A Zavoriti, Q Pucelle… - Physiological …, 2022 - Wiley Online Library
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

Muscle fibre activation and fatigue with low‐load blood flow restricted resistance exercise—an integrative physiology review

M Wernbom, P Aagaard - Acta physiologica, 2020 - Wiley Online Library
Blood flow‐restricted resistance exercise (BFRRE) has been shown to induce increases in
muscle size and strength, and continues to generate interest from both clinical and basic …

Acute cellular and molecular responses and chronic adaptations to low-load blood flow restriction and high-load resistance exercise in trained individuals

CJ Davids, TC Næss, M Moen… - Journal of applied …, 2021 - journals.physiology.org
Blood flow restriction (BFR) with low-load resistance exercise (RE) is often used as a
surrogate to traditional high-load RE to stimulate muscular adaptations, such as hypertrophy …