Immunological effects of human milk oligosaccharides

V Triantis, L Bode, RJJ Van Neerven - Frontiers in pediatrics, 2018 - frontiersin.org
Human milk oligosaccharides (HMOs) comprise a group of structurally complex,
unconjugated glycans that are highly abundant in human milk. HMOs are minimally digested …

Human milk oligosaccharides: every baby needs a sugar mama

L Bode - Glycobiology, 2012 - academic.oup.com
Human milk oligosaccharides (HMOs) are a family of structurally diverse unconjugated
glycans that are highly abundant in and unique to human milk. Originally, HMOs were …

From carbohydrate leads to glycomimetic drugs

B Ernst, JL Magnani - Nature reviews Drug discovery, 2009 - nature.com
Carbohydrates are the most abundant natural products. Besides their role in metabolism
and as structural building blocks, they are fundamental constituents of every cell surface …

Early life: gut microbiota and immune development in infancy

R Martin, AJ Nauta, KB Amor, L Knippels, J Knol… - Beneficial …, 2010 - brill.com
The immune system of infants is actively downregulated during pregnancy and therefore the
first months of life represent a period of heightened susceptibility to infection. After birth …

Diversity of human milk oligosaccharides and effects on early life immune development

V Ayechu-Muruzabal, AH Van Stigt, M Mank… - Frontiers in …, 2018 - frontiersin.org
One of the well-known features of human milk, is the capacity to protect against the risk and
impact of neonatal infections, as well as to influence the onset of allergic and metabolic …

Non-digestible carbohydrates in infant formula as substitution for human milk oligosaccharide functions: Effects on microbiota and gut maturation

R Akkerman, MM Faas, P de Vos - Critical Reviews in Food …, 2019 - Taylor & Francis
Human milk (HM) is the golden standard for nutrition of newborn infants. Human milk
oligosaccharides (HMOs) are abundantly present in HM and exert multiple beneficial …

[HTML][HTML] Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years …

S Arslanoglu, GE Moro, J Schmitt, L Tandoi… - The Journal of …, 2008 - Elsevier
A mixture of neutral short-chain galactooligosaccharides (scGOS) and long-chain
fructooligosaccharides (lcFOS) has been shown to reduce the incidence of atopic dermatitis …

Human milk oligosaccharides: prebiotics and beyond

L Bode - Nutrition reviews, 2009 - academic.oup.com
Human milk oligosaccharides (HMO) are complex glycans that are present at very high
concentrations in human milk but not in infant formula. The significant energy expended by …

Direct evidence for the presence of human milk oligosaccharides in the circulation of breastfed infants

KC Goehring, AD Kennedy, PA Prieto, RH Buck - PloS one, 2014 - journals.plos.org
Background It has been hypothesized that human milk oligosaccharides (HMOs) confer
systemic health benefits to breastfed infants; however, plausible mechanisms for some …

Human milk oligosaccharides as promising antivirals

V Morozov, G Hansman, FG Hanisch… - Molecular nutrition & …, 2018 - Wiley Online Library
Human milk oligosaccharides (HMOs) are diverse unconjugated carbohydrates that are
highly abundant in human breast milk. These glycans are investigated in the context of …