Cigarette smoking and e-cigarette use induce shared DNA methylation changes linked to carcinogenesis

C Herzog, A Jones, I Evans, JR Raut, M Zikan… - Cancer Research, 2024 - AACR
Tobacco use is a major modifiable risk factor for adverse health outcomes, including cancer,
and elicits profound epigenetic changes thought to be associated with long-term cancer risk …

Multi-view clustering for integration of gene expression and methylation data with tensor decomposition and self-representation learning

X Gao, Y Wang, W Hou, Z Liu… - IEEE/ACM Transactions on …, 2022 - ieeexplore.ieee.org
The accumulated DNA methylation and gene expression provide a great opportunity to
exploit the epigenetic patterns of genes, which is the foundation for revealing the underlying …

EpigenPlot: An interactive web platform for DNA methylation‐based biomarker and drug target discovery in colorectal cancer

D Müller, B Győrffy - British Journal of Pharmacology, 2025 - Wiley Online Library
Abstract Background and Purpose Genome‐wide methylation studies have significantly
advanced our understanding of colorectal adenocarcinoma progression and biomarker …

Four methylation-driven genes detected by linear discriminant analysis model from early-stage colorectal cancer and their methylation levels in cell-free DNA

L Zhan, C Sun, Y Zhang, Y Zhang, Y Jia, X Wang… - Frontiers in …, 2022 - frontiersin.org
The process of colorectal cancer (CRC) formation is considered a typical model of
multistage carcinogenesis in which aberrant DNA methylation plays an important role. In this …

[Retracted] Analysis of Rural Tourism and Environmental Influencing Factors Based on Analytic Hierarchy Model

N Guo - Wireless Communications and Mobile Computing, 2022 - Wiley Online Library
This research focuses on the analytic hierarchy model in the decision‐making system that
has a more complex structure and maintains the stability of the system, models the …

Epigenetic Conservation Infers That Colorectal Cancer Progenitors Retain The Phenotypic Plasticity Of Normal Colon

K Street, K Siegmund, D Shibata - 2023 - researchsquare.com
Plasticity, or the ability to rapidly and reversibly change phenotypes, may help explain how a
single progenitor cell eventually generates a tumor with many different cell phenotypes. We …