Recent advances in natural polymer-based drug delivery systems

X Tong, W Pan, T Su, M Zhang, W Dong, X Qi - Reactive and Functional …, 2020 - Elsevier
Natural polymers have been extensively explored as the vehicles for encapsulation and
delivery of drugs and other bioactive molecules, which have attracted tremendous attention …

Cationic polymers as transfection reagents for nucleic acid delivery

X Cai, R Dou, C Guo, J Tang, X Li, J Chen, J Zhang - Pharmaceutics, 2023 - mdpi.com
Nucleic acid therapy can achieve lasting and even curative effects through gene
augmentation, gene suppression, and genome editing. However, it is difficult for naked …

Engineering siRNA therapeutics: challenges and strategies

SS Ali Zaidi, F Fatima, SA Ali Zaidi, D Zhou… - Journal of …, 2023 - Springer
Small interfering RNA (siRNA) is a potential method of gene silencing to target specific
genes. Although the US Food and Drug Administration (FDA) has approved multiple siRNA …

Gene therapy for regenerative medicine

H Hosseinkhani, AJ Domb, G Sharifzadeh, V Nahum - Pharmaceutics, 2023 - mdpi.com
The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

Research status and prospect of non-viral vectors based on siRNA: a review

L Tong, D Liu, Z Cao, N Zheng, C Mao, S Liu… - International journal of …, 2023 - mdpi.com
Gene therapy has attracted much attention because of its unique mechanism of action, non-
toxicity, and good tolerance, which can kill cancer cells without damaging healthy tissues …

Generation of scaffold incorporated with nanobioglass encapsulated in chitosan/chondroitin sulfate complex for bone tissue engineering

BN Singh, V Veeresh, SP Mallick, S Sinha… - International journal of …, 2020 - Elsevier
Over the past decade, various composite materials fabricated using natural or synthetic
biopolymers incorporated with bioceramic have been widely investigated for the …

Fabrication and characterization of Spinacia oleracea extract incorporated alginate/carboxymethyl cellulose microporous scaffold for bone tissue engineering

G Sharmila, C Muthukumaran, S Kirthika… - International journal of …, 2020 - Elsevier
In recent years, plant based scaffold due to its inherent properties such as mechanical
stability, renewability, easy mass production, inexpensiveness, biocompatibility and …

[图书][B] Biomedical Engineering: Materials, Technology, and Applications

H Hosseinkhani - 2022 - books.google.com
Biomedical Engineering An exploration of materials processing and engineering technology
across a wide range of medical applications The field of biomedical engineering has played …

Lipid nanoparticle-encapsulated VEGFa siRNA facilitates cartilage formation by suppressing angiogenesis

Y Chen, W Chen, Y Ren, S Li, M Liu, J Xing… - International Journal of …, 2022 - Elsevier
Cartilage is an important tissue that is widely found in joints, ears, nose and other organs.
The limited capacity to regenerate makes cartilage reconstruction an urgent clinical demand …

Transient receptor potential vanilloid 1: A potential therapeutic target for the treatment of osteoarthritis and rheumatoid arthritis

Z Liao, M Umar, X Huang, L Qin, G Xiao… - Cell …, 2024 - Wiley Online Library
This study aims to determine the molecular mechanisms and analgesic effects of transient
receptor potential vanilloid 1 (TRPV1) in the treatments of osteoarthritis (OA) and rheumatoid …