More than just a barrier: the immune functions of the airway epithelium in asthma pathogenesis

A Frey, LP Lunding, JC Ehlers, M Weckmann… - Frontiers in …, 2020 - frontiersin.org
Allergic bronchial asthma is a chronic disease of the airways that is characterized by
symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute …

The canyon hypothesis

MG Rossmann - Viral immunology, 1989 - liebertpub.com
The three-dimensional structure of human rhinovirus 14 has a deep surface depression or"
canyon" encircling each of the twelve fivefold vertices. The canyon's surface is inaccessible …

[图书][B] Fields' virology

BN Fields - 2007 - books.google.com
Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

CL Mendelsohn, E Wimmer, VR Racaniello - Cell, 1989 - cell.com
Restriction of poliovirus replication to a few sites in the infected primate host appears to be
controlled by the expression of viral receptors. To learn more about these binding sites and …

The three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution

R Acharya, E Fry, D Stuart, G Fox, D Rowlands… - Nature, 1989 - nature.com
The structure of foot-and-mouth disease virus has been determined at close to atomic
resolution by X-ray diffraction without experimental phase information. The virus shows …

The three-dimensional structure of canine parvovirus and its functional implications

J Tsao, MS Chapman, M Agbandje, W Keller, K Smith… - Science, 1991 - science.org
The three-dimensional atomic structure of a single-stranded DNA virus has been
determined. Infectious virions of canine parvovirus contain 60 protein subunits that are …

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

JH Condra, WA Schleif, OM Blahy, LJ Gabryelski… - Nature, 1995 - nature.com
INHIBITORS of the human immunodeficiency virus type 1 (HIV-1) protease have entered
clinical study as potential therapeutic agents for HIV-1 infection. The clinical efficacy of HIV-1 …

The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

DE Staunton, ML Dustin, HP Erickson, TA Springer - Cell, 1990 - cell.com
Summary Intercellular adhesion molecule 1 (ICAM-1, CD54) binds to the integrin LFA-1
(CDlla/CD18), promoting cell adhesion in immune and inflammatory reactions. ICAM-is also …

Respiratory syncytial virus

CB Hall - Principles and practice of clinical virology, 1999 - Wiley Online Library
Respiratory synctial virus (RSV) infections are a common and concerning conundrum. This
ubiquitous agent is the major respiratory pathogen of young children, with life‐threatening …

Picornaviruses

TJ Tuthill, E Groppelli, JM Hogle… - Cell Entry by Non …, 2010 - Springer
The picornavirus family consists of a large number of small RNA viruses, many of which are
significant pathogens of humans and livestock. They are amongst the simplest of vertebrate …