Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …

As one of the most important cancer treatment strategies, conventional chemotherapy has
substantial side effects and leads easily to cancer treatment failure. Therefore, exploring and …

Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Polymer nanoparticles (NPs) represent one of the most innovative non-invasive approaches
for drug delivery applications. NPs main objective is to convey the therapeutic molecule be …

P-glycoprotein (P-gp), an efflux membrane transporter, is widely distributed throughout the
body and is responsible for limiting cellular uptake and the distribution of xenobiotics and …

Nanomedicine of synergistic drug combinations has shown increasing significance in
cancer therapy due to its promise in providing superior therapeutic benefits to the current …

The use of multiple therapeutic agents in combination has become the primary strategy to
treat drug resistant cancers. However, administration of combinatorial regimens is limited by …

With growing interest in cancer therapeutics, anti-angiogenic therapy has received
considerable attention and is widely administered in several types of human cancers …