Diffuse correlation spectroscopy (DCS) uses the temporal fluctuations of near-infrared (NIR)
light to measure cerebral blood flow (CBF) non-invasively. Here, we provide a brief history of …

The vascular network delivers oxygen (O2) and nutrients to all cells within the body. It is
therefore not surprising that O2 availability serves as a primary regulator of this complex …

Peripheral arterial disease (PAD) usually results from atherosclerosis and associated
thrombosis and limits blood supply to the lower limbs. Common presenting symptoms …

We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse
correlation spectroscopy (DCS) measurements. The new formulation enables blood flow …

Light propagating in tissue attains a spectrum that varies with location due to wavelength-
dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption …

Localized tissue hypoxia is a consequence of vascular compromise or rapid cellular
proliferation and is a potent inducer of compensatory angiogenesis. The oxygen-responsive …

Diffuse optics has proven useful for quantitative assessment of tissue oxy-and
deoxyhaemoglobin concentrations and, more recently, for measurement of microvascular …

In this study we evaluate the influences of optical property assumptions on near-infrared
diffuse correlation spectroscopy (DCS) flow index measurements. The optical properties …

A primary focus of neurointensive care is the prevention of secondary brain injury, mainly
caused by ischemia. A noninvasive bedside technique for continuous monitoring of cerebral …

Deeper insight into the molecular pathways that orchestrate skeletal myogenesis should
enhance our understanding of, and ability to treat, human skeletal muscle disease. It is now …