Lipids are one of the major components of biological membranes including the plasma
membrane, which is the interface between the cell and the environment. It has become clear …

1.1. Background Beginning in the early 1980s, cell biologists started realising that some
phospholipids are not just basic constituents of membranes but dynamic informational …

A large part (about 70%) of the surface of the earth is covered by oceans that comprise a salt
solution with an osmotic potential of about 2.0 MP, derived primarily from sodium and …

Lowe syndrome, also known as oculocerebrorenal syndrome, is caused by mutations in the
X chromosome-encoded OCRL gene. The OCRL protein is 51% identical to inositol …

All things flow and change… even in the stillest matter there is unseen flux and movement.
Attributed to Heraclitus (530–470 BC) From The Story of Philosophy by Will Durant …

Plant signal perception and transduction The discovery of the mammalian phosphoinositide
signalling system has led to tremendous progress in the understanding of how extracellular …

We have isolated additional cDNA clones encoding type II inositol polyphosphate 5-
phosphatase (5-phosphatase II) resulting in a combined cDNA of 3076 nucleotides …

SAC (for suppressor of actin) domain proteins in yeast and animals have been shown to
modulate the levels of phosphoinositides, thereby regulating several cellular activities such …

The plant plasma membrane (PM) H+‐ATPase is an essential enzyme controlling plant
growth and development. It is an important factor in response to abiotic and biotic stresses …

The yeast protein Sac1p is involved in a range of cellular functions, including inositol
metabolism, actin cytoskeletal organization, endoplasmic reticulum ATP transport …