Eukaryotic core promoters and the functional basis of transcription initiation
Abstract RNA polymerase II (Pol II) core promoters are specialized DNA sequences at
transcription start sites of protein-coding and non-coding genes that support the assembly of …
transcription start sites of protein-coding and non-coding genes that support the assembly of …
Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Structural insights into preinitiation complex assembly on core promoters
INTRODUCTION RNA polymerase II (Pol II)–mediated transcription initiation requires
assembly of a preinitiation complex (PIC), during which the 14-subunit transcription factor IID …
assembly of a preinitiation complex (PIC), during which the 14-subunit transcription factor IID …
Enhancer–core-promoter specificity separates developmental and housekeeping gene regulation
MA Zabidi, CD Arnold, K Schernhuber, M Pagani… - Nature, 2015 - nature.com
Gene transcription in animals involves the assembly of RNA polymerase II at core promoters
and its cell-type-specific activation by enhancers that can be located more distally. However …
and its cell-type-specific activation by enhancers that can be located more distally. However …
The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription
O Mikhaylichenko, V Bondarenko… - Genes & …, 2018 - genesdev.cshlp.org
Gene expression is regulated by promoters, which initiate transcription, and enhancers,
which control their temporal and spatial activity. However, the discovery that mammalian …
which control their temporal and spatial activity. However, the discovery that mammalian …
The RNA polymerase II core promoter
ST Smale, JT Kadonaga - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The events leading to transcription of eukaryotic protein-coding genes culminate
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
Cis-regulatory elements used to control gene expression in plants
R Biłas, K Szafran, K Hnatuszko-Konka… - Plant Cell, Tissue and …, 2016 - Springer
Plant biotechnology is a dynamically developing science, which comprises many fields of
knowledge. Novel plant genetic engineering findings highly influence the improvement of …
knowledge. Novel plant genetic engineering findings highly influence the improvement of …
The general transcription machinery and general cofactors
MC Thomas, CM Chiang - Critical reviews in biochemistry and …, 2006 - Taylor & Francis
In eukaryotes, the core promoter serves as a platform for the assembly of transcription
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
[HTML][HTML] Regulation of gene expression via the core promoter and the basal transcriptional machinery
T Juven-Gershon, JT Kadonaga - Developmental biology, 2010 - Elsevier
The RNA polymerase II core promoter is a structurally and functionally diverse
transcriptional regulatory element. There are two main strategies for transcription initiation …
transcriptional regulatory element. There are two main strategies for transcription initiation …
The RNA polymerase II core promoter: a key component in the regulation of gene expression
JEF Butler, JT Kadonaga - Genes & development, 2002 - genesdev.cshlp.org
The development, growth, and survival of eukaryotic organisms require the proper
regulation of tens of thousands of genes. By complex formulae that have yet to be solved …
regulation of tens of thousands of genes. By complex formulae that have yet to be solved …