The hypusine-containing translation factor eIF5A

TE Dever, E Gutierrez, BS Shin - Critical reviews in biochemistry …, 2014 - Taylor & Francis
In addition to the small and large ribosomal subunits, aminoacyl-tRNAs, and an mRNA,
cellular protein synthesis is dependent on translation factors. The eukaryotic translation …

Role of eIF5A in mitochondrial function

M Barba-Aliaga, P Alepuz - International journal of molecular sciences, 2022 - mdpi.com
The eukaryotic translation initiation factor 5A (eIF5A) is an evolutionarily conserved protein
that binds ribosomes to facilitate the translation of peptide motifs with consecutive prolines or …

[PDF][PDF] Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard

TC Terwilliger, PD Adams, RJ Read… - … Section D: Biological …, 2009 - journals.iucr.org
Estimates of the quality of experimental maps are important in many stages of structure
determination of macromolecules. Map quality is defined here as the correlation between a …

[PDF][PDF] Maximum-likelihood density modification

TC Terwilliger - Acta Crystallographica Section D: Biological …, 2000 - journals.iucr.org
A likelihood-based approach to density modification is developed that can be applied to a
wide variety of cases where some information about the electron density at various points in …

[PDF][PDF] Automated main-chain model building by template matching and iterative fragment extension

TC Terwilliger - Acta Crystallographica Section D: Biological …, 2003 - journals.iucr.org
An algorithm for the automated macromolecular model building of polypeptide backbones is
described. The procedure is hierarchical. In the initial stages, many overlapping polypeptide …

SOLVE and RESOLVE: automated structure solution and density modification

TC Terwilliger - Methods in enzymology, 2003 - Elsevier
Publisher Summary The software packages SOLVE and RESOLVE comprise a suite for an
automated structure solution using multiple isomorphous replacement (MIR) …

The weird and wonderful world of bacterial ribosome regulation

DN Wilson, KH Nierhaus - Critical reviews in biochemistry and …, 2007 - Taylor & Francis
In every organism, translation of the genetic information into functional proteins is performed
on the ribosome. In Escherichia coli up to 40% of the cell's total energy turnover is …

[HTML][HTML] Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes

G Lipowsky, FR Bischoff, P Schwarzmaier… - The EMBO …, 2000 - embopress.org
Transport receptors of the importin β superfamily account for many of the nuclear import and
export events in eukaryotic cells. They mediate translocation through nuclear pore …

Posttranslational Protein Modification in Archaea

J Eichler, MWW Adams - Microbiology and Molecular Biology …, 2005 - Am Soc Microbiol
One of the first hurdles to be negotiated in the postgenomic era involves the description of
the entire protein content of the cell, the proteome. Such efforts are presently complicated by …

Structural and mechanistic conservation in DNA ligases

AJ Doherty, SW Suh - Nucleic acids research, 2000 - academic.oup.com
DNA ligases are enzymes required for the repair, replication and recombination of DNA.
DNA ligases catalyse the formation of phosphodiester bonds at single-strand breaks in …