Molecular mechanism of β-sitosterol and its derivatives in tumor progression

X Bao, Y Zhang, H Zhang, L Xia - Frontiers in oncology, 2022 - frontiersin.org
β-Sitosterol (SIT), a white powdery organic substance with a molecular formula of C29H50O,
is one of the most abundant naturally occurring phytosterols in plants. With a chemical …

Anticancer activity and other biomedical properties of β‐sitosterol: Bridging phytochemistry and current pharmacological evidence for future translational approaches

S Nandi, A Nag, S Khatua, S Sen… - Phytotherapy …, 2024 - Wiley Online Library
Sterols, including β‐sitosterol, are essential components of cellular membranes in both plant
and animal cells. Despite being a major phytosterol in various plant materials …

Beta sitosterol and Daucosterol (phytosterols identified in Grewia tiliaefolia) perturbs cell cycle and induces apoptotic cell death in A549 cells

T Rajavel, R Mohankumar, G Archunan, K Ruckmani… - Scientific reports, 2017 - nature.com
Lung cancer is the leading cause of cancer related deaths both in developed and
developing countries. Since majority of the existing therapeutic methods harms both normal …

Virgin coconut oil: A comprehensive review of antioxidant activity and mechanisms contributed by phenolic compounds

YQ Zeng, JT He, BY Hu, W Li, J Deng… - Critical Reviews in …, 2024 - Taylor & Francis
Virgin coconut oil (VCO) is obtained by processing mature coconut cores with mechanical or
natural methods. In recent years, VCO has been widely used in the food, pharmaceutical …

Towards a better understanding of Fagopyrum dibotrys: a systematic review

LL Zhang, Y He, F Sheng, YF Hu, Y Song, W Li… - Chinese Medicine, 2021 - Springer
Abstract Fagopyrum dibotrys (F. dibotrys)(D. Don) H. Hara is a well-known edible herbal
medicine in Asian countries. It has been widely used for the treatment of lung diseases …

The Genus Alternanthera: Phytochemical and Ethnopharmacological Perspectives

RK Singla, V Dhir, R Madaan, D Kumar… - Frontiers in …, 2022 - frontiersin.org
Ethnopharmacological relevance: The genus Alternanthera (Amaranthaceae) comprises
139 species including 14 species used traditionally for the treatment of various ailments …

A review on application of nanoparticles in cEOR: Performance, mechanisms, and influencing parameters

D Kumar, N Lashari, T Ganat, MA Ayoub… - Journal of Molecular …, 2022 - Elsevier
Various chemical additives used in chemical enhanced oil recovery (cEOR) boost
hydrocarbon recovery due to their incredible potential for changing critical reservoir …

Conformational characterization of the co-activator binding site revealed the mechanism to achieve the bioactive state of FXR

A Kumari, L Mittal, M Srivastava, DP Pathak… - Frontiers in Molecular …, 2021 - frontiersin.org
FXR bioactive states are responsible for the regulation of metabolic pathways, which are
modulated by agonists and co-activators. The synergy between agonist binding and 'co …

[HTML][HTML] Molecular dynamics simulation reveals the possible druggable hot-spots of USP7

M Srivastava, C Suri, M Singh, R Mathur, S Asthana - Oncotarget, 2018 - ncbi.nlm.nih.gov
Abstract The plasticity in Ubiquitin Specific Proteases (USP7) inducing conformational
changes at important areas has highlighted an intricate mechanism, by which USP7 is …

Therapeutic and diagnostic applications of carbon nanotubes in cancer: recent advances and challenges

M Sharma, P Alessandro… - Journal of Drug …, 2024 - Taylor & Francis
Carbon nanotubes (CNTs) are allotropes of carbon, composed of carbon atoms forming a
tube-like structure. Their high surface area, chemical stability, and rich electronic …