Viral–bacterial co-infections in the respiratory tract

LO Bakaletz - Current opinion in microbiology, 2017 - Elsevier
Highlights•Viruses predispose to secondary bacterial infection throughout the respiratory
tract.•Viral damage to airway epithelium and aberrant inflammatory responses play key …

[HTML][HTML] Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

S Manna, P Baindara, SM Mandal - Journal of Infection and Public Health, 2020 - Elsevier
Secondary bacterial infections are commonly associated with prior or concomitant
respiratory viral infections. Viral infections damage respiratory airways and simultaneously …

Herpes simplex virus and cytomegalovirus reactivations among severe COVID-19 patients

P Le Balc'h, K Pinceaux, C Pronier, P Seguin, JM Tadié… - Critical Care, 2020 - Springer
Methods We reviewed all virology results for patients admitted to Rennes University Hospital
(Rennes, France) for COVID-19 ARDS between March 3, 2020, and April 15, 2020. SARS …

Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality

I Gatto, E Biagioni, I Coloretti, C Farinelli, C Avoni… - Intensive care …, 2022 - Springer
Purpose Cytomegalovirus (CMV) reactivation in immunocompetent critically ill patients is
common and relates to a worsening outcome. In this large observational study, we …

[HTML][HTML] Antimicrobial stewardship in the ICU in COVID-19 times: the known unknowns

J Schouten, J De Waele, C Lanckohr, D Koulenti… - International Journal of …, 2021 - Elsevier
Since the start of the COVID-19 pandemic, there has been concern about the concomitant
rise of antimicrobial resistance (AMR). While bacterial co-infections seem rare in COVID-19 …

Effect of ganciclovir on IL-6 levels among cytomegalovirus-seropositive adults with critical illness: a randomized clinical trial

AP Limaye, RD Stapleton, L Peng, SR Gunn… - Jama, 2017 - jamanetwork.com
Importance The role of cytomegalovirus (CMV) reactivation in mediating adverse clinical
outcomes in nonimmunosuppressed adults with critical illness is unknown. Objective To …

Pneumonia with bacterial and viral coinfection

K Cawcutt, AC Kalil - Current opinion in critical care, 2017 - journals.lww.com
Bacterial and viral coinfection is increasingly recognized as an underlying etiology for
community-and hospital-acquired infections. Coinfections may be a risk factor for ICU …

A practical review of cytomegalovirus in gastroenterology and hepatology

AY Fakhreddine, CT Frenette… - … research and practice, 2019 - Wiley Online Library
Human cytomegalovirus (CMV) is a ubiquitous Herpesviridae virus with a wide spectrum of
pathology in humans. Host immunity is a major determinant of the clinical manifestation of …

[HTML][HTML] Cytomegalovirus infection in critically ill patients with COVID-19

T Niitsu, T Shiroyama, H Hirata, Y Noda… - The Journal of …, 2021 - ncbi.nlm.nih.gov
We read with great interest the systematic review by Alene et al. 1 and the comment on it by
Cao et al., 2 who pooled data of the incidence rate of depression in patients with …

Etiology of sepsis in Uganda using a quantitative polymerase chain reaction-based TaqMan array card

CC Moore, ST Jacob, P Banura, J Zhang… - Clinical Infectious …, 2019 - academic.oup.com
Background Knowledge of causes of sepsis in sub-Saharan Africa is limited. A better
understanding of the microbiology of bloodstream infections could improve outcomes …