Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …

Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …

Lifestyle choices, external environment, aging, and other factors influence the synthesis of
melatonin. Although the physiological functions of melatonin have been widely studied in …

Background Chemotherapy-related cognitive impairment (CRCI) is highly prevalent in
patients with cancer and is associated with poor outcomes and quality of life. To date, the …

Due to the negative roles of tumor microenvironment (TME) in compromising therapeutic
responses of various cancer therapies, it is expected that modulation of TME may be able to …

Chemotherapy treatment is associated with acute behavioral side effects (fatigue, anorexia)
that significantly reduce patient quality of life and are dose-limiting, thereby increasing …

Psychological disorders are associated with increased risk of severe inflammatory bowel
disease (IBD) by causing gut microbiota dysbiosis and colonic mucosal barrier damage …

The current study investigated the positive effects of blueberry anthocyanin-rich extracts
(BAE) on either peripheral or hippocampal antioxidant defensiveness and established the …

Cancer affects more than 19.3 million people and has become the second leading cause of
death worldwide. Chemo-and radiotherapy, the most common procedures in these patients …

Background Chemotherapy-induced peripheral neuropathy (CIPN) is a severe dose-limiting
side effect of chemotherapy and remains a huge clinical challenge. Here, we explore the …