Emerging non-viral vectors for gene delivery

C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …

Progress in polymer single-chain based hybrid nanoparticles

Y Shao, Z Yang - Progress in Polymer Science, 2022 - Elsevier
Precise control of molecular hierarchical organization has endowed biological systems with
unique functions, which inspires great efforts in the synthesis of artificial mimics. Polymeric …

A hybrid injectable hydrogel from hyperbranched PEG macromer as a stem cell delivery and retention platform for diabetic wound healing

Q Xu, A Sigen, Y Gao, L Guo, J Creagh-Flynn, D Zhou… - Acta biomaterialia, 2018 - Elsevier
The injectable hydrogel with desirable biocompatibility and tunable properties can improve
the efficacy of stem cell-based therapy. However, the development of injectable hydrogel …

Complex polymer architectures through free-radical polymerization of multivinyl monomers

Y Gao, D Zhou, J Lyu, Q Xu, B Newland… - Nature Reviews …, 2020 - nature.com
The construction of complex polymer architectures with well-defined topology, composition
and functionality has been extensively explored as the molecular basis for the development …

Polymer gene delivery: overcoming the obstacles

A Aied, U Greiser, A Pandit, W Wang - Drug discovery today, 2013 - Elsevier
Highlights•Minor modifications to polymer structure determine transfection
properties.•Efficient gene delivery requires timely release of DNA.•Serum stability is …

Exploiting the Monomer-Feeding Mechanism of RAFT Emulsion Polymerization for Polymerization-Induced Self-Assembly of Asymmetric Divinyl Monomers

J Zhou, Q Huang, L Zhang, J Tan - ACS Macro Letters, 2023 - ACS Publications
We exploited the monomer-feeding mechanism of reversible addition–fragmentation chain
transfer (RAFT) emulsion polymerization to achieve the successful polymerization-induced …

Catechol functionalized hyperbranched polymers as biomedical materials

H Zhang, T Zhao, B Newland, W Liu, W Wang… - Progress in Polymer …, 2018 - Elsevier
The catechol plays a variety of important roles in biological processes, prompting
researchers to include them in the design of biomimetic biomedical materials. The low …

Active kinetic chain length: guide for control in atom transfer radical polymerization

J Lyu, Y Li, Z Li, M Johnson, S Sosnowski… - Chemical Engineering …, 2023 - Elsevier
Since atom transfer radical polymerization (ATRP) was developed, various strategies have
been adopted to design well-controlled ATRP procedures. However, there is no single …

Biomaterials applications of cyclic polymers

B Golba, EM Benetti, BG De Geest - Biomaterials, 2021 - Elsevier
Cyclic polymers are an intriguing class of polymers due to their lack of chain ends. This
unique architecture combined with steric constraints adorn cyclic polymers as well as nano …

All-silicone 3D printing technology: toward highly elastic dielectric elastomers and complex structures

C Tugui, M Cazacu, DM Manoli, A Stefan… - ACS Applied Polymer …, 2023 - ACS Publications
Silicone elastomers have been shown to be well-suited for dielectric elastomer actuators
(DEA), mainly due to their unique combination of properties such as, high elasticity and …